Urinary angiotensinogen predicts adverse outcomes among acute kidney injury patients in the intensive care unit

Table 2 Summary of performance characteristics of urinary angiotensinogen as a predictor of outcomes among acute kidney injury patients

Outcome	AUC^a	Cutoff (ng/mg)	Sensitivity	Specificity
RRT or death^b	0.73 (0.58 to 0.88)	Best: > 34.76	78.3%	54.6%
		Max LR+: > 230.0	43.5%	95.5%
		Min LR-: ≤ 7.58	95.7%	31.8%
LOS^c	0.77 (0.63 to 0.92)	Best: > 59.61	60.6%	83.3%
		Max LR+: > 123.5	43.5%	95.5%
		Min LR-: ≤ 3.31	97.1%	25.0%
Worsening AKI^d	0.77 (0.63 to 0.91)	Best: > 34.76	87.0%	63.6%
		Max LR+: > 230.0	39.1%	90.9%
		Min LR-: ≤ 21.24	95.7%	59.1%

^aAUC, area under the receiver operator characteristic curve; ^bRRT, renal replacement therapy; ^cLOS, length of hospital stay (days after sample collection); ^dworsening acute kidney injury (AKI) defined as an increase in serum creatinine > 0.3 mg/dL after sample collection or initiation of RRT; LR, likelihood ratio; Max, maximum; Min, minimum.

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