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Table 2 Summary of performance characteristics of urinary angiotensinogen as a predictor of outcomes among acute kidney injury patients

From: Urinary angiotensinogen predicts adverse outcomes among acute kidney injury patients in the intensive care unit

Outcome AUCa Cutoff (ng/mg) Sensitivity Specificity
RRT or deathb 0.73
(0.58 to 0.88)
Best: > 34.76 78.3% 54.6%
   Max LR+: > 230.0 43.5% 95.5%
   Min LR-: ≤ 7.58 95.7% 31.8%
LOSc 0.77
(0.63 to 0.92)
Best: > 59.61 60.6% 83.3%
   Max LR+: > 123.5 43.5% 95.5%
   Min LR-: ≤ 3.31 97.1% 25.0%
Worsening AKId 0.77
(0.63 to 0.91)
Best: > 34.76 87.0% 63.6%
   Max LR+: > 230.0 39.1% 90.9%
   Min LR-: ≤ 21.24 95.7% 59.1%
  1. aAUC, area under the receiver operator characteristic curve; bRRT, renal replacement therapy; cLOS, length of hospital stay (days after sample collection); dworsening acute kidney injury (AKI) defined as an increase in serum creatinine > 0.3 mg/dL after sample collection or initiation of RRT; LR, likelihood ratio; Max, maximum; Min, minimum.