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Table 1 Characteristics of ICU patients used to verify the prognostic predictive power of urinary angiotensinogen as an acute kidney injury biomarker

From: Urinary angiotensinogen predicts adverse outcomes among acute kidney injury patients in the intensive care unit

  No RRT and Survival RRT or Death P-value
Number of patients 22 23  
Age, yrsa 62.9 ± 16.1 54.4 ± 17.6 0.1
Caucasian, % (n) 64 (14) 65 (15) 0.84
Male, % (n) 55 (12) 65 (15) 0.67
AKI etiology, n (%)    
Sepsis 23 (5) 43 (10) 0.25
Pre-renal 32 (7) 4 (1) 0.01
Ischemic ATN 9 (2) 13 (3) 1
Other 36 (8) 39 (9) 0.91
Serum creatinine (sCr), mg/dL    
Baseline sCrb 1.15 (0.8, 1.6) 1.1 (1.0, 1.5) 0.98
sCr at collectiona 2.1 ± 0.8 2.5 ± 0.8 0.06
Change in sCrb, % 150 (130 to 189) 200 (150 to 257) 0.07
AKIN stage at collection    0.14
Stage 1 17 11  
Stage 2 4 8  
Stage 3 1 4  
Outcomes, % patients (n)    
RRT 0 52 (12) < 0.001
Death 0 78 (18) < 0.001
Other variables    
MAP on day of collectionb 74.9 (70.4 to 86.8) 68.6 (64.5 to 84.1) 0.08
History of HTN, % patients (n) 91 (20) 48 (11) 0.005
History of diabetes mellitus, % patients (n) 55 (12) 22 (5) 0.05
History of ACE inhibitor or ARB use, % patients (n) 48 (12) 17 (4) 0.03
  1. aMean ± SD; bmedian and IQR; categorical data are shown as percentage and number. P-values are shown for the χ2 or Fisher exact test, as appropriate. RRT, renal replacement therapy; AKI, acute kidney injury; ATN, Acute tubular necrosis}; AKIN, Acute Kidney Injury Network; MAP, Mean arterial pressure}; HTN, Hypertension}; ARB, Angiotensin receptor blocker}.