Table 1 Characteristics of ICU patients used to verify the prognostic predictive power of urinary angiotensinogen as an acute kidney injury biomarker
No RRT and Survival | RRT or Death | P-value | |
|---|---|---|---|
Number of patients | 22 | 23 | |
Age, yrsa | 62.9 ± 16.1 | 54.4 ± 17.6 | 0.1 |
Caucasian, % (n) | 64 (14) | 65 (15) | 0.84 |
Male, % (n) | 55 (12) | 65 (15) | 0.67 |
AKI etiology, n (%) | |||
Sepsis | 23 (5) | 43 (10) | 0.25 |
Pre-renal | 32 (7) | 4 (1) | 0.01 |
Ischemic ATN | 9 (2) | 13 (3) | 1 |
Other | 36 (8) | 39 (9) | 0.91 |
Serum creatinine (sCr), mg/dL | |||
Baseline sCrb | 1.15 (0.8, 1.6) | 1.1 (1.0, 1.5) | 0.98 |
sCr at collectiona | 2.1 ± 0.8 | 2.5 ± 0.8 | 0.06 |
Change in sCrb, % | 150 (130 to 189) | 200 (150 to 257) | 0.07 |
AKIN stage at collection | 0.14 | ||
Stage 1 | 17 | 11 | |
Stage 2 | 4 | 8 | |
Stage 3 | 1 | 4 | |
Outcomes, % patients (n) | |||
RRT | 0 | 52 (12) | < 0.001 |
Death | 0 | 78 (18) | < 0.001 |
Other variables | |||
MAP on day of collectionb | 74.9 (70.4 to 86.8) | 68.6 (64.5 to 84.1) | 0.08 |
History of HTN, % patients (n) | 91 (20) | 48 (11) | 0.005 |
History of diabetes mellitus, % patients (n) | 55 (12) | 22 (5) | 0.05 |
History of ACE inhibitor or ARB use, % patients (n) | 48 (12) | 17 (4) | 0.03 |