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Table 1 Patients' characteristics before and after inverse probability weighting

From: Timing of renal replacement therapy initiation by AKIN classification system

   Before weighting After inverse probability of treatment weighting
  AKI
( n = 150)
ED group
( n = 64)
LD group
( n = 86)
Standardized difference P -value Standardized difference P -value
Age, years 55.5 ± 19.1 54.6 ± 19.7 56.2 ± 18.4 0.08 0.604 0.09 0.586
Sex, male, n (%) 84 (57.5) 35 (54.7) 51 (59.3) 0.09 0.539 0.01 0.960
Diabetes mellitus, n (%) 34 (22.7) 14 (21.9) 20 (23.2) 0.03   0.05 0.812
Hypertension, n (%) 67 (44.7) 27 (42.1) 40 (46.5) 0.09   0.07 0.698
Lower sCr, mg/dL 0.90 ± 0.30 0.96 ± 0.30 0.87 ± 0.29 0.29 0.056 0.03 0.849
Surgical ICU admission, n (%) 27 (18.0) 32 (50) 45 (52.3) 0.04 0.778 0.13 0.409
Sepsis diagnosed, n (%) 129 (86.0) 56 (87.5) 73 (84.9) 0.07 0.648 0.13 0.402
Data at ICU admission        
Vasoactive drugs, n (%) 116 (77.3) 49 (76.6) 67 (77.9) 0.03 0.846 0.15 0.338
Systolic blood pressure, mmHg 101.0 ± 22.9 91.8 ± 20.2 108.6 ± 22.5 0.73 0.001 0.17 0.174
Diastolic blood pressure, mmHg 59.4 ± 14.9 55.5 ± 13.4 62.5 ± 15.3 0.13 0.033 0.14 0.201
Heart rate, bpm 101.1 ± 23.5 104.7 ± 21.5 99.3 ± 24.8 0.23 0.160 0.02 0.872
Hemoglobin, g/dL 10.1 ± 2.2 9.8 ± 2.4 10.5 ± 2.1 0.29 0.069 0.14 0.367
White blood cells, x103/mm3 17.0 ± 8.6 15.9 ± 6.6 17.5 ± 7.4 0.07 0.643 0.11 0.659
Platelet count, x103/mm3 230.4 ± 121.7 235.3 ± 131.2 226.4 ± 120.2 0.06 0.724 0.15 0.349
Creatinine, mg/dL 2.11 ± 1.22 2.0 ± 0.9 1.7 ± 0.8 0.04 0.791 0.11 0.357
Urea, mg/dL 78.7 ± 43.1 82.7 ± 44.1 75.4 ± 41.8 0.12 0.481 0.09 0.560
Potassium, mEq/L 4.4 ± 2.1 4.7 ± 1.4 4.2 ± 0.9 0.14 0.394 0.03 0.494
Bicarbonate, mEq/L 17.7 ± 5.7 16.7 ± 5.5 18.5 ± 5.9 0.30 0.071 0.19 0.250
GCS score 12.8 ± 2.7 12.8 ± 3.1 12.8 ± 2.5 0.01 0.986 0.17 0.331
APACHE II score 18.8 ± 6.1 19.2 ± 6.3 18.7 ± 5.9 0.08 0.520 0.03 0.848
SAPS III score 61.1 ± 11.9 62.1 ± 11.7 60.2 ± 12.0 0.15 0.327 0.20 0.227
Data at RRT start        
Creatinine, mg/dL 2.93 ± 1.82 2.7 ± 1.1 2.8 ± 1.5 0.04 0.780 0.03 0.855
Urea, mg/dL 106.7 ± 64.8 100.1 ± 54.9 108.2 ± 55.6 0.17 0.461 0.02 0.908
Potassium, mEq/L 5.3 ± 2.0 4.9 ± 1.9 5.1 ± 2.1 0.11 0.499 0.15 0.392
Bicarbonate, mEq/L 16.2 ± 4.4 14.4 ± 3.9 17.2 ± 4.3 0.64 < 0.0001 0.14 0.501
APACHE II score 20.2 ± 6.3 20.3 ± 6.8 20.1 ± 6.2 0.06 0.637 0.05 0.737
SAPS III score 62.6 ± 12.3 63.2 ± 11.8 62.7 ± 11.6 0.10 0.469 0.14 0.298
Indications for dialysis        
Azotemia, n (%) 27 (18.0) 7 (10.9) 20 (23.3) 0.34 0.052 0.06 0.715
Oligoanuria, n (%) 118 (78.7) 53 (82.8) 65 (75.6) 0.18 0.285 0.20 0.305
Metabolic acidosis, n (%) 96 (64.0) 46 (71.9) 50 (58.1) 0.29 0.083 0.17 0.358
Hyperkalemia, n (%) 21 (14.0) 4 (6.2) 17 (19.8) 0.41 0.018 0.13 0.402
  1. Results are presented as mean (± SD) unless or number (%) of patients. AKI, acute kidney injury; CKD, chonic kidney disease; RRT, renal replacement therapy GCS, Glascow Coma Scale; APACHE, Acute Physiology and Chronic Health Evaluation; SAPS, Simplified Acute physiology Score; sCr, serum creatinine; ED, early dialysis; LD, late dialysis.