Table 2 Bleeding characteristics and treatments administered to the 15 patients
Parameter | Value | |
|---|---|---|
Site of bleeding | Â | Â |
   Venoarterial ECMO |  |  |
Mediastinal (post-surgery) | 11 (73.3) | |
   Venovenous ECMO |  |  |
Mediastinal (post-surgery) | 1 | |
Hemothorax | 1 | |
Gynecologic | 1 | |
Epistaxis | 1 | |
Transfusion required | Â | Â |
   Packed red blood cell | 17 (13.5-19) | |
   Fresh-frozen plasma | 14 (9-21.5) | |
   Concentrated platelets | 5 (3-8) | |
Biologic parameters before and after rFVIIa infusion | Before | After |
   Hemoglobin | 7.5 (7.1-8.6) | 9 (8.2-9.8) |
   Platelets | 83 (61-117) | 68 (61-106) |
   PT | 46 (42-52) | 101 (54-120) |
   aPTT | 1.7 (1.4-2.2) | 1.4 (1.2-1.9) |
   Ionized calcemia | 1.10 (1.05-1.20) | 1.17 (1.03-1.28) |
   pH | 7.37 (7.28-7.42) | 7.41 (7.34-7.47) |
Temperature before rFVIIa infusion (°C) | 36.4 (34.3-37.1) | |
rFVIIa dose infused (μg/kg) | 77 (54-144) | |
Number of injections of rFVIIa, number of patients | Â | Â |
   1 | 10 | |
   2 | 3 | |
   3 | 1 | |
   4 | 1 | |