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Table 3 Multivariate logistic regression analysis of blood markers (natural log-transformed) between favorable and poor outcome groups

From: Predictive value of circulating interleukin-6 and heart-type fatty acid binding protein for three months clinical outcome in acute cerebral infarction: multiple blood markers profiling study

  OR (95% CI) P Adjusted ORa P
Neuronal markers     
   NSE 1.23 (0.89 - 1.68) 0.209 0.79 (0.49 - 1.26) 0.325
   Ngb 1.73 (1.28 - 2.34) 0.0004 1.41 (0.89 - 2.24) 0.143
   hFABP 4.90 (2.67 - 9.00) < 0.0001 3.23 (1.44 - 7.27) 0.0045
   VSNL-1b 1.26 (0.38 - 4.14) 0.704 0.87 (0.19 - 4.02) 0.854
Astroglial markers     
   S100B 1.60 (1.39 - 1.92) < 0.0001 1.20 (0.96 - 1.51) 0.115
   GFAPb 2.79 (1.42 - 5.49) 0.003 1.15 (0.41 - 3.22) 0.791
Inflammatory markers     
   IL-6 2.23 (1.68 - 2.95) < 0.0001 1.75 (1.25 - 2.25) 0.001
   TNF-α 1.22 (0.94 - 1.57) 0.134 1.35 (0.88 - 2.05) 0.166
   CRP 1.63 (1.33 - 1.99) < 0.0001 1.23 (0.94 - 1.62) 0.148
Blood-brain barrier marker     
   MMP-9 2.19 (1.43 - 3.44) 0.005 1.65 (1.07 - 2.07) 0.014
Haemostatic markers     
   PAI-1 1.05 (0.79 - 1.38) 0.748 1.07 (0.71 - 1.61) 0.751
   D-dimer 2.49 (1.61 - 3.86) < 0.0001 1.37 (0.74 - 2.57) 0.319
  1. The favorable group is regarded as the reference (OR: 1.0). aAdjustment of age and initial NIHSS score; bcategorical variables. CI, confidence interval; CRP, C-reactive protein; GFAP, glial fibrillary acidic protein; hFABP, heart type fatty acid binding protein; MMP-9 matrix metalloproteinase-9; Ngb, neuroglobin; NSE, neuron-specific enolase; OR, odds ratio; PAI-1, plasminogen activator inhibitor-1; VSNL-1, visinin-like protein 1.