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Table 1 Characteristics of the study population (n = 69)

From: Effect of angiotensin-converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome

Age (years)

64.4 ± 17.9; 69 (28 to 89)

Sex (males, %)

43 (62.3%)

APACHE II score

22.1 ± 6.2; 21 (14 to 35)

SOFA score

8.4 ± 3.2; 8 (4 to 16)

Lung compliance (ml/cmH2O)

29.4 ± 7.2; 30 (17 to 40)

PaO2/FiO2

139, 1 ± 47.1; 140 (72 to 223)

PEEP

8.1 ± 2.9; 8 (5 to 15)

Lung Injury Score

2.5 ± 0.6; 2.5 (1.75 to 3.50)

Blood lactate (mmol/l)

1.7 ± 1.7; 1.3 (0.5 to 5.2)

Septic status

39 (56.5%)

Serum ACE (U/l)

16.5 ± 10.8; 13.6 (4.8 to 39.8)

BALF (U/l)

2.3 ± 1.4; 2.0 (0.3 to 4.7)

ACE I/D polymorphism:

 

   D/D

27 (39.1%)

   I/D

28 (40.6%)

   I/I

14 (20.3%)

28-day mortality

34/69 (49.3%)

90-day mortality

43/69 (62.3%)

Ventilator-free days

5.1 ± 7.8; (0 to 23)

Days w/o cardiovascular failure

14.0 ± 10.2; 16 (0 to 27)

Days w/o renal failure

15.4 ± 10.6; 16 (0 to 28)