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Table

From: Sepsis progression is associated with a gradual depletion of both insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP3) and a progressive elevation of growth hormone (GH) serum levels

 

Normal

Sepsis

Severe sepsis

Septic shock

P

GH (ng/Ml)

1.12 ± 0.56

5.58 ± 0.27

2.3 ± 1.1

6.3 ± 1.9b

0.013884

IGF-I (ng/mL)

170.9 ± 18.3

124.3 ± 18.6

91.7 ± 24.2

62.1 ± 7.6a,b

0.000163

IGHBP-3 (μg/Ml)

2.98 ± 0.14

1.98 ± 0.19a

1.73 ± 0.46a

1.38 ± 0.15a

0.000002

  1. Data are mean ± standard error of mean, astatistically different from normal, bstatistically different from sepsis.
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Critical Care

ISSN: 1364-8535