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Table 2 Differences between control group and complete intervention group

From: Haloperidol prophylaxis in critically ill patients with a high risk for delirium

 

Control

group

(N= 299)

Intervention group

(N= 177)

Differences

(P-value)

Predicted delirium chance

73 ± 22

75 ± 19

0.50

Observed delirium incidence (n,%)

225 (75%)

115 (65%)

0.01

Non-delirium:

74 (25%)

62 (35%)

0.38

Delirium subtype:

   

   - Hyperactive

20 (7%)

6 (3%)

 

   - Hypoactive

81 (27%)

33 (19%)

 

   - Mixed

124 (41%)

76 (43%)

 

Number of delirium free days without coma in 28 days

13 (3 to 27)

20 (8 to 27)

0.003

Re-intubation (%)

25 (8%)

15 (9%)

0.51

Duration mechanical ventilation in hrs.

118 (39 to 250)

90 (36 to 229)

0.24

Unplanned removal tubes/lines (%)

58 (19%)

21 (12%)

0.02

   - Tube

8 (3%)

4 (2%)

 

   - Gastric tube

26 (9%)

14 (8%)

 

   - CVC/arterial line

24 (8%)

1 (<1%)

 

   - Other

0 (0%)

2 (1%)

 

Re-admission

55 (18%)

20 (11%)

0.03

LOS-ICU

7 (3 to 13)

6 (3 to 12)

0.65

LOS-in hospital

21 (12 to 41)

20 (11 to 31)

0.16

28-day mortality

36 (12%)

13 (7.3%)

0.03*

  1. Data are presented as median, interquartile range (IQR), unless mentioned otherwise. * Cox proportional hazard regression analysis adjusted for sepsis and cohort (hazard rate 0.80; 95% CI 0.66 to 0.98.