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Figure 2 | Critical Care

Figure 2

From: Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study

Figure 2

Lower bacterial outgrowth in protease-activated receptor-1 knockout mice in lungs and blood at 24 hours and in spleen and liver at 48 hours after induction of murine pneumococcal pneumonia. Bacterial outgrowth in (A) lung, (B) blood, (C) spleen and (D) liver 6, 24, and 48 hours after induction of pneumococcal pneumonia in wild-type (open bars) and protease-activated receptor-1 knockout (grey bars) mice. Data are expressed as box-and-whisker diagrams depicting the smallest observation, lower quartile, median, upper quartile and largest observation (eight mice per group). * indicates statistical significance as compared to wild-type (P <0.05, Mann-Whitney U test).

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Critical Care

ISSN: 1364-8535