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Table 2 Multivariate analysis of characteristics associated with mortality

From: Brain-derived neurotrophic factor plasma levels are associated with mortality in critically ill patients even in the absence of brain injury

 

OR (CI 95%)

P value

Model 1

  

BDNF 25th quartile

12.7 (2.2 to 73)

0.004

Sepsis

6.3 (1.1 to 39)

0.04

Age

1.01 (0.98 to 1.06)

0.33

Admission SOFA

1.06 (0.87 to 1.31)

0.53

Mechanical ventilation

8.56 (0.92 to 79)

0.05

Model 2

  

BDNF D2

29 (4 to 200)

0.001

Sepsis

3.3 (0.56 to 20)

0.18

Age

1.04 (0.99 to 1.09)

0.09

Admission SOFA

0.91 (0.72 to 1.15)

0.46

Mechanical ventilation

14 (1.1 to 175)

0.038

  1. Hosmer and Lemershow goodness-of-fit model 1, χ2 = 2.2; P = 0.97; and model 2, χ2 = 1.9; P = 0.98. BDNF D2, brain-derived neurotrophic factor collected 48 hours after intensive care admission; CI, confidence interval; OR, odds ratio; SOFA, sequential organ-failure assessment.