Skip to main content

Table 2 Frequency of dementia diagnoses in three years of follow-up by characteristics from the index hospitalization.

From: Risk factors for dementia after critical illness in elderly medicare beneficiaries

 

Total Cohort, number

Dementia in 3 years follow-up, number (%)

HR

(95% CI)

P Value

Total cohort

25,368

4,519 (17.8)

   

   Surgical

12,740

1,780 (14.0)

1 (ref)

-

-

   Medical

12,628

2,739 (21.7)

1.75

(1.65, 1.85)

< .01

Mechanical Ventilation

     

   None

23,067

4,108 (17.8)

1 (ref)

-

-

   < 96 hours

1,716

301 (17.5)

1.09

(0.97, 1.22)

0.17

   ≥ 96 hours

585

110 (18.8)

1.25

(1.05, 1.49)

0.01

No Acute RRT

25,094

4,453 (17.8)

-

-

-

Acute RRT

274

66 (24.1)

1.61

(1.26, 2.05)

< .01

No Infection

17,151

2,783 (16.2)

1 (ref)

-

-

Infection onlya

5,072

1,053 (20.8)

1.44

(1.34, 1.54)

< .01

Severe sepsis

3,145

683 (21.7)

1.63

(1.50, 1.77)

< .01

Acute Organ Dysfunction

     

None

19,165

3,289 (17.2)

1 (ref)

-

-

One

5,003

973 (19.5)

1.25

(1.16, 1.34)

< .01

Two or more

1,200

257 (21.4)

1.43

(1.26, 1.62)

< .01

   Specific Organ Dysfunctionb

     

Cardiac

1,888

351 (18.6)

1.08

(0.97, 1.20)

0.18

Respiratory

2,164

394 (18.2)

1.17

(1.05, 1.30)

< .01

Renal

2,194

464 (21.2)

1.37

(1.24, 1.51)

< .01

Neurologic

351

130 (37.0)

2.38

(2.00, 2.84)

< .01

Encephalopathy

144

53 (36.8)

-

-

-

Delirium

167

68 (40.7)

-

-

-

Anoxia

48

12 (27.1)

-

-

-

Hematologic

940

176 (18.7)

1.12

(0.96, 1.30)

0.14

ICU length of stay (quartiles)c

     

1

8,255

1,290 (15.6)

1 (ref)

-

-

2

5,349

977 (18.3)

1.23

(1.13, 1.34)

.04

3

6,748

1,270 (18.8)

1.31

(1.21, 1.41)

.11

4

4,953

971 (19.6)

1.44

(1.33, 1.57)

< .01

Hospital length of stay (quartiles)d

     

1

7,201

1,068 (14.7)

1 (ref)

-

-

2

6,848

1,218 (17.8)

1.30

(1.20, 1.41)

< .01

3

5,640

1,085 (19.2)

1.47

(1.35, 1.60)

< .01

4

5,679

1,156 (20.4)

1.70

(1.56, 1.84)

< .01

  1. aBacterial or fungal infection but without acute organ failure (that is, no diagnosis of severe sepsis); bhepatic failure, as a subtype of acute organ dysfunction, is not shown because of low frequency. The reference group for each of the five subtypes is everyone without that dysfunction; cmissing data on 63 patients; dhospital length of stay includes ICU days. HR, hazard ratio; ref, reference; RRT, renal replacement therapy.
Back to article page

Critical Care

ISSN: 1364-8535