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Table 4 Antibiotic prescription in patients treated with DCCT or non-DCCT

From: Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality

Antibiotics

Non-DCCT group

n= 984 (71.7%)

DCCT group

n= 388 (28.3%)

P

β-Lactams

582 (59.1%)

320 (82.5%)

<0.001

Carbapenems

269 (27.3%)

76 (19.6%)

0.003

Quinolones

96 (9.8%)

186 (47.9%)

<0.001

Aminoglycosides

25 (2.5%)

158 (40.7%)

<0.001

Macrolides

7 (0.7%)

53 (13.7%)

<0.001

Anti-gram-positive

120 (12.2%)

41 (10.6%)

0.456

Antifungals

21 (2.1%)

17 (4.4%)

0.028

Others

121 (12.3%)

30 (7.7%)

0.016