Figure 3

Mean Clinical Pulmonary Infection Scores (CPIS) for the MITT treatment groups during antibiotic therapy. Error bars displayed are based on the 95% confidence interval around the means. As there is significant dropout over time, as can be seen by the available sample sizes at the bottom of the figure, the results have to be interpreted with caution. Nevertheless, the curves suggest that the patients' improvement is similar for the two treatment arms up to Day 8 (the last day of active doripenem treatment), where after the decreasing trend is continued for the subjects in the Imipenem-cilastatin arm (who receive active treatment up to Day 11), but remains stable for subjects in the doripenem arm (who receive only placebo from Day 9 up to Day 11).