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Table 3 Independent factors associated with 100-day survival, by multivariate Cox proportional hazards regression analysis

From: Empirical use of fluoroquinolones improves the survival of critically ill patients with tuberculosis mimicking severe pneumonia

 

Patients (n)

Mortality within 100 days, n(%)

Median survival of fatal cases (days)

P value

Hazards ratio

95% confidence interval

Age

      

   ≥70

60

34 (56.7)

50

0.32

1.75

0.58 to 5.31

   <70

17

6 (35.3)

16

   

APACHE score

      

   ≥20

52

33 (63.5)

36

0.01

3.75

1.34 to 10.44

   <20

25

7 (28.0)

100

   

SOFA score

      

   ≥8

35

19 (54.3)

44

0.21

1.63

0.76 to 3.49

   <8

41

20 (48.8)

100

   

Empiric antibiotic

      

   Fluoroquinolone

43

17 (39.5)

46

<0.01

0.36

0.17 to 0.77

   Nonfluoroquinolone

34

23 (67.6)

60

   

Bacteremia in the ICU

      

   Yes

11

9 (81.8)

46

<0.01

3.88

1.64 to 9.19

   No

66

31 (47.0)

49

   

TB study in the ICU within 1 week

     

   Yes

67

36 (53.7)

47.5

0.22

1.99

0.66 to 5.99

   No

10

4 (40.0)

48.5

   

Initiation of ATT in ICU within 2 weeks

     

   Yes

18

10 (55.6)

68.5

0.53

1.38

0.50 to 3.84

   No

44

17 (38.6)

40

   
  1. APACHE, Acute Physiology and Chronic Health Evaluation score; ATT, anti-tuberculosis treatment; SOFA, Sequential Organ Failure Assessment score; TB, tuberculosis.
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Critical Care

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