Background
Advances in modern medicine and patient management have seen increased use of prosthetic materials, leading to biofilm formation, and the constituent organisms are different in their growth rates and susceptibility patterns and cause many complications. Candida species are increasingly seen to be important nosocomial pathogens and are major causes of morbidity and mortality in immunocompromised patients of intensive care and postoperative wards. Hence our aims were to isolate and identify specific Candida species associated with the luminal biofilm in endotracheal tubes/i.v. catheters in ICU patients and to study the pathogenicity of Candida species by testing for virulence mechanisms including biofilm formation and antifungal susceptibility.