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Table 3 Demographics and clinical characteristics of the test cohort

From: The pediatric sepsis biomarker risk model

 

All

Survivors

Non-survivors

Number of subjects

135

117

18

Median age in years (25%, 75%)

2.8 (1.0, 6.7)

2.7 (1.0, 6.7)

3.8 (0.9, 7.7)

Median PRISM score (25%, 75%)

13 (7, 19)

12 (7, 18)

23 (14, 32)1

Number of males (%)

70 (52)

63 (54)

7 (39)

Number of females (%)

65 (48)

54 (46)

11 (61)

Number for race (%)

   

   Caucasian

113 (84)2

99 (85)

14 (78)

   African American

15 (11)

13 (11)

2 (11)

   Other3

6 (4)

4 (3)

2 (11)

   Unreported

1 (1)2

1 (1)

0 (0)

Number with gram (+) bacteria (%)

27 (20)2

24 (21)

3 (17)

Number with gram (-) bacteria (%)

27 (20)

22 (19)

5 (28)

Number with viral infection (%)

10 (7)

9 (8)

1 (6)

Number with fungal infection (%)

2 (1)

2 (2)

0 (0)

Number with no organism isolated (%)

72 (53)2

63 (54)

9 (50)

Number with any co-morbidity (%)

52 (39)

45 (38)

7 (39)4

Number with meningitis (%)

5 (4)

3 (3)

2 (11)

Number with cancer (%)

17 (13)

14 (12)

3 (17)

Number with immune suppression (%) 5

13 (10)

13 (11)

0 (0)

  1. 1P = 0.001 vs. survivors. 2P <0.05 for test cohort vs. derivation cohort. 3Includes Asian, multi-racial, native Hawaiian/Pacific Islander, and American Indian. 4Co-morbidities in non-survivors included acute myeloid leukemia; atrial and ventricular septal defects; fulminant hepatic failure; hypoplastic left heart syndrome; short gut syndrome; neuroblastoma; and optic nerve glioma. 5Refers to patients with immune suppression not related to cancer (for example, those receiving immune suppressive medication for solid organ transplantation, or those with a primary immune deficiency).