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Table 2 Characteristics and outcomes of patients according to degree of proteinuria (n = 396)

From: Relation between proteinuria and acute kidney injury in patients with severe burns

 

None

(n= 125)

Mild

(n= 180)

Heavy

(n= 91)

P-value

Age (years)

38 (16.00)

42 (16.75)

41 (15.00)

0.050

Gender (% of males)

72.80

83.89

86.81

0.150

TBSA (%)

38 (15.50)

54.4 (35.00)

70 (41.00)

< 0.001

dTBSA (%)

35 (13.50)

48 (33.00)

60 (39.00)

< 0.001

Escharotomy (%)

3 (15.50)

9 (27.75)

24 (38.00)

< 0.001

Electrical injury (%)

7.20

7.22

10.99

0.511

Chemical injury (%)

24.00

17.88

10.99

0.049

Inhalation injury (%)

25.60

46.67

48.35

< 0.001

Comorbidities (%)

1.60

9.44

7.69

0.042

ACS (%)

3.20

17.78

25.78

< 0.001

Vasopressor in first 48 h (%)

0.80

6.67

7.69

0.030

Artificial colloid (%)

38.46

53.72

53.85

0.341

Albumin (%)

57.69

34.71

32.05

0.540

Urine output at shock stage (%, ≥ 0.5 ml/Kg·h-1)

97.60

75.00

64.84

< 0.001

Nephrotoxic drugs (%)

23.08

51.24

55.13

0.015

Length of mechanical ventilation (days)

0 (0.00)

0 (2.00)

1 (6.00)

> 0.001

Sepsis during ICU stay (%)

15.20

46.11

67.03

< 0.001

Positive blood culture (%)

54.51

58.37

87.12

< 0.001

Gram-positive bacteria (%)

9.68

51.61

38.71

< 0.001

Gram-negative bacteria (%)

23.53

50.00

26.47

< 0.001

Positive culture, others (%)

0.00

51.56

48.44

< 0.001

Maximum RIFLE

   

< 0.001

No AKI (%, n = 245)

51.02

36.73

12.24

< 0.001

Risk (%, n = 83)

0.00

61.45

38.55

< 0.001

Injury (%, n = 52)

0.00

61.54

38.46

< 0.001

Failure (%, n = 16)

0.00

43.75

56.25

< 0.001

Maximum SOFA

0 (0.00)

4 (7.00)

6 (8.00)

< 0.001

CRRT during ICU stay (%)

0.00

5.00

7.69

< 0.001

Length of CRRT treatment (days)

0 (0.00)

0 (0.00)

0 (2.00)

0.013

ICU length of stay (days)

0 (0.00)

2 (30.00)

4 (49.00)

< 0.001

ICU mortality (%)

0.8

16.67

30.77

< 0.001

  1. ACS, abdominal compartment syndrome; CRRT, continuous renal replacement therapy; dTBSA, total surface area of deep second degree or third degree burn; ICU, intensive care unit; RIFLE, Risk, Injury, Failure, Loss, End Stage classification; SOFA, sequential organ failure assessment; TBSA, total burn surface area. Continuous variables, median (quartile range); categorical variables, (%).
  2. Variables coding: Maximum RIFLE 1: No-AKI, 2: Risk, 3: Injury, 4: Failure + loss + end stage