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Figure 1 | Critical Care

Figure 1

From: Bench-to-bedside review: Citrate for continuous renal replacement therapy, from science to practice

Figure 1

Comparison of the intracellular calcium increase ([Ca2+]i) in isolated leukocytes after in vitro stimulation with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) at different extracellular calcium concentrations with and without citrate. Green, 1 mmol/l EGTA, creating [ecCa2+] < 0.025 mmol/L; blue, 0.1 mmol ecCa2+/L; red, 4 mmol citrate/L added to a 1.75 mmol ecCa2+/L solution; black, 1.75 mmol ecCa2+/L. [Heemskerk JW, Feijge MA, Oudemans-van Straaten HM]

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