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Figure 6 | Critical Care

Figure 6

From: RETRACTED ARTICLE: Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis

Figure 6

Effects of diacerhein treatment on the JNK pathway signaling in the CLP rat. Representative blots show the JNK phosphorylation, total protein expression of JNK, and serine 307 phosphorylation of IRS1 in liver (A), adipose tissue (B), and muscle (C) of sham and septic rats. Blots were stripped and reprobed with β-actin (lower panels) to confirm equal loading of proteins. Data are presented as mean ± SEM from six to eight rats per group. *P < 0.05 versus Sham/Vehicle; #P < 0.05 (Sepsis/Veh versus Sepsis/Dia). IB, immunoblot; Sham, Sham/Vehicle; Sham+Dia, Sham/Diacerhein; Sepsis, Sepsis/Vehicle; Sepsis+Dia, Sepsis/Diacerhein.

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Critical Care

ISSN: 1364-8535