Figure 1
Effect of minute ventilation during oxygen-induced hypercapnia. During 15 minutes of high oxygen administration, an initial decrease in minute ventilation, which recovers substantially, is seen in patients with acute exacerbation of chronic obstructive pulmonary disease. However, the oxygen-induced hypercapnia does not recover. CO2, carbon dioxide; VE, minute ventilation. Based on data of Aubier and colleagues [4].