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Table 3 Positive predictive value (PPV) and negative predictive value (NPV) for assessing the prognostic utility of the baseline values of cfDNA and other variables

From: Prognostic utility and characterization of cell-free DNA in patients with severe sepsis

Variable Positive predictive value 95% CI Likelihood ratio
χ2
Negative predictive value 95% CI Likelihood ratio
χ2
cfDNA 0.91 0.81-1.00 25.64 0.91 0.83-1.00 37.80
APACHE II 0.55 0.42-0.69 0.64 0.88 0.74-1.00 15.19
MODS 0.65 0.45-0.85 2.16 0.67 0.54-0.79 6.46
Age 0.53 0.39-0.68 0.19 0.73 0.57-0.88 7.07
TAT complexes 0.59 0.40-0.77 0.87 0.65 0.52-0.79 4.67
Protein C 0.64 0.43-0.84 1.66 0.66 0.53-0.78 5.68
IL-6 0.86 0.59-1.00 3.96 0.61 0.50-0.73 3.59
Female gender 0.44 0.30-0.57 0.89 0.60 0.40-0.80 1.01