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Table 1 Patient characteristics in included trials

From: Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis

      

Illness Acuity

     

Trial

Patients,n

Centers,n

Age,yr

Male%

Surg%

APACHE II

SAPS II

MODS or SOFA

Ventilated%

Vasopressors%

Oliguria,

%

Cr,μM

Urea,mM

Sepsis,%

Mortality a,%

Parallel Group

               

Davenport 1993 [21] (medians)

20

1

33

45%

 

28

  

100%

 

100%b

646

18

 

84% h

Alamartine 1994 [22]

13

1

n/r

n/r

 

22

     

566

30

 

n/a

Pettila 2001 [23]

39

1

48

82%

 

20

 

10 MODS

95%

 

61%c

446

31

 

42%

Morgera 2004 [24] (medians)

24

1

65

58%

 

31

     

254

44

 

50% (ICU)

Daud 2006 [25] (medians)

20

2

50

60%

  

66

 

100%

  

265

19

90%

85% (ICU)

Saudan 2006 [26]

206

1

63

61%

 

25

 

9 SOFA

  

37%d

428

30

60%

53% (90d)

Chang 2009j [27]

96

1

65

57%

 

31

 

13 SOFA

   

238

19

100%

54% (28d)

Ratanarat 2009k [28]

17

1

65

           

n/c

Ratanarat 2012 [29]

60

1

57

60%

0%

27

  

93%

67%

 

449

32

82%

47% (28d)

OMAKI 2012 [30]

77

6

61

61%

   

16 SOFA

95%

90%

 

261

22

82%

55%

Crossover

               

Maher 1988 [31]

5

1

median 51

100%

    

80%

100%

     

Alarabi 1992 [32]

13

1

60

62%

38%

   

92%

100%

 

453

36

  

Jeffery 1994 [33]

10

1

             

Kellum 1998 [34]

13 (10)e

1

           

100%

77(70) %e

Garcia-Fernandez 2000 [35]

40

1

60

65%

38%

   

58%

53%

70%i

  

48%

48%

Maxvold 2000 [36]

6

1

11

33%

17%

    

100%

    

50% ( undef)

Wynkel 2004 [37]

18

1

62

 

39%

 

60g

       

50% (30d)

Ricci 2006 [38] (medians)

15

1

50

67%

60%

 

61

        

Davies 2008 [39]

45 (31)f

1

61 (57)

64% (77%)

38%

26

         
  1. Means, (medians where noted). aHospital mortality except where noted. Oliguria: b<10 mL/h [21], c<500 mL/24h [23], d<200 mL/12 h [26], and i<400 mL/24h [34]. eFor Kellum 1998 [34], 3/13 patients died prior to being crossed over to other arm. fFor Davies 2008 [39], 45 patients were randomized but only 31 patients crossed over and received both therapies. gWynkel 2004 [37] excluded SAPS II >= 85. hMortality obtained after author contact [21]. jChang 2009 [27] reported data from 65 patients in abstract form; data for 31 patients who were subsequently randomized provided after author contact. kAuthor informed us that mortality was not recorded [28]. Abbreviations: APACHE II, acute physiology and chronic health evaluation II [63]; Cr, serum creatinine concentration in micromoles per litre; MODS, multiple organ dysfunction score [66]; n/a, not available after author contact; n/c, not collected; n/r, not reported; SAPS II, simplified acute physiology score II [64]; SOFA, sequential organ failure assessment score [65].