Histology of liver and lung damage 24 hours after CLP with and without rhDNase treatment. (A) Histology of lung obtained from sham mice. (B) Representative CLP-induced lung damage. (C) Representative lung of CLP mice treated with rhDNase (CLP + rhDNase). (D) Histology of liver obtained from sham mice. (E) Representative CLP-induced liver damage. (F) Representative liver of CLP mice treated with rhDNase (CLP + rhDNase). Sham and CLP mice were sacrificed 24 hours after surgery. Original magnification, ×10. CLP, cecal ligation and puncture; DNase, desoxyribonuclease; rh, recombinant human.