Table 1 Characteristics of the study sample, comparing intensive care unit survivors and nonsurvivors
From: Ventilatory support in critically ill hematology patients with respiratory failure
Overall n= 300 | Survivors n= 93 | Nonsurvivors n= 207 | Pvalue | |
|---|---|---|---|---|
Age, years (SD) | 53.6 (16.7) | 54.9 (14.6) | 53.5 (17.5) | 0.50 |
Women (%) | 112 (37.5) | 41 (36.6) | 71 (63.4) | 0.12 |
APACHE II (SD) | 24.8 (8.3) | 22.18 (7.4) | 25.9 (8.3) | 0.001 |
Main diagnosis (%) | 0.79 | |||
Acute leukemia | 127 (44.7) | 37 (39.8) | 90 (43.4) | |
Chronic leukemia | 33 (11.6) | 9 (9.7) | 24 (11.6) | |
Hodgkin lymphoma | 13 (4.3) | 3 (3.2) | 10 (4.8) | |
Non-Hodgkin lymphoma | 76 (26.7) | 26 (28) | 50 (24.2) | |
Multiple myeloma | 19 (6.3) | 8 (8.6) | 11 (5.3) | |
Myelodysplastic syndrome | 10 (3.3) | 2 (2.1) | 8 (3.9) | |
Other | 22 (7.3) | 8 (8.6) | 14 (6.8) | |
HSCT (%) | 0.06 | |||
No | 229 (76.3) | 74 (79.6) | 155 (74.9) | |
Autologous | 26 (8.7) | 11 (11.8) | 15 (7.2) | |
Allogeneic | 45 (15) | 8 (8.6) | 37 (17.9) | |
Neutropenia (%) | 129 (15) | 42 (32.6) | 87 (67.4) | 0.26 |
Diagnosis on ICU admission (%) | ||||
Shock | 81 (27) | 18 (19.4) | 63 (30.4) | 0.05 |
Infection (other than pneumonia) | 100 (33) | 35 (37.6) | 65 (31.4) | 0.29 |
Pneumonia | 112 (37.3) | 35 (37.6) | 77 (37.2) | 0.22 |
Other causes of respiratory failure | 83 (27.6) | 21 (22.6) | 62 (30) | 0.19 |
Congestive heart failure | 20 (6.7) | 8 (8.6) | 12 (5.8) | 0.01 |
Coma | 14 (4.7) | 3 (3.2) | 11 (5.3) | 0.51 |
Other | 52 (17.3) | 11 (11.8) | 41 (19.8) | 0.70 |
Bacteremia on admission (%) | 95 (31.7) | 31 (33.3) | 64 (30.9) | 0.68 |
Initial ventilatory support (%) | 0.17 | |||
IMV | 169 (56.3) | 47 (50.5) | 122 (58.9) | |
NIMV | 131 (43.7) | 46 (49.5) | 85 (41.1) | |
NIMV failure | 79 (26.3) | 16 (17.2) | 63 (30.4) | <0.001 |
In-hospital days before ICU admission, days (SD) | 14.7 (17.3) | 15.2 (17.4) | 13.4 (16.8) | 0.42 |
Length of ICU stay, days (SD) | 11.7 (13.2) | 15.7 (16.6) | 9.8 (11.0) | <0.001 |