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Table 1 Characteristics of the study sample, comparing intensive care unit survivors and nonsurvivors

From: Ventilatory support in critically ill hematology patients with respiratory failure

  Overall
n= 300
Survivors
n= 93
Nonsurvivors
n= 207
Pvalue
Age, years (SD) 53.6 (16.7) 54.9 (14.6) 53.5 (17.5) 0.50
Women (%) 112 (37.5) 41 (36.6) 71 (63.4) 0.12
APACHE II (SD) 24.8 (8.3) 22.18 (7.4) 25.9 (8.3) 0.001
Main diagnosis (%)     0.79
   Acute leukemia 127 (44.7) 37 (39.8) 90 (43.4)  
   Chronic leukemia 33 (11.6) 9 (9.7) 24 (11.6)  
   Hodgkin lymphoma 13 (4.3) 3 (3.2) 10 (4.8)  
   Non-Hodgkin lymphoma 76 (26.7) 26 (28) 50 (24.2)  
   Multiple myeloma 19 (6.3) 8 (8.6) 11 (5.3)  
   Myelodysplastic syndrome 10 (3.3) 2 (2.1) 8 (3.9)  
   Other 22 (7.3) 8 (8.6) 14 (6.8)  
HSCT (%)     0.06
   No 229 (76.3) 74 (79.6) 155 (74.9)  
   Autologous 26 (8.7) 11 (11.8) 15 (7.2)  
   Allogeneic 45 (15) 8 (8.6) 37 (17.9)  
Neutropenia (%) 129 (15) 42 (32.6) 87 (67.4) 0.26
Diagnosis on ICU admission (%)     
   Shock 81 (27) 18 (19.4) 63 (30.4) 0.05
   Infection (other than pneumonia) 100 (33) 35 (37.6) 65 (31.4) 0.29
   Pneumonia 112 (37.3) 35 (37.6) 77 (37.2) 0.22
   Other causes of respiratory failure 83 (27.6) 21 (22.6) 62 (30) 0.19
   Congestive heart failure 20 (6.7) 8 (8.6) 12 (5.8) 0.01
   Coma 14 (4.7) 3 (3.2) 11 (5.3) 0.51
   Other 52 (17.3) 11 (11.8) 41 (19.8) 0.70
Bacteremia on admission (%) 95 (31.7) 31 (33.3) 64 (30.9) 0.68
Initial ventilatory support (%)     0.17
   IMV 169 (56.3) 47 (50.5) 122 (58.9)  
   NIMV 131 (43.7) 46 (49.5) 85 (41.1)  
NIMV failure 79 (26.3) 16 (17.2) 63 (30.4) <0.001
In-hospital days before ICU admission, days (SD) 14.7 (17.3) 15.2 (17.4) 13.4 (16.8) 0.42
Length of ICU stay, days (SD) 11.7 (13.2) 15.7 (16.6) 9.8 (11.0) <0.001
  1. Values are given as number (%) or mean (SD). HSTC, hematopoietic stem cell transplantation; IMV, invasive mechanical ventilation; NIMV, noninvasive mechanical ventilation.