Figure 1From: Identification of haplotype tag single nucleotide polymorphisms within the receptor for advanced glycation end products gene and their clinical relevance in patients with major traumaOverview of selected tSNPs within the entire RAGE gene. (A) The pair-wise analysis of linkage disequilibrium (LD), based on r2, among the 10 SNPs with a minor allele frequency ³5% within the RAGE gene and 505 bp up- and 5,000 bp down-stream regions. The selected tSNPs are indicated by trigones. A LD-plot of the 10 SNPs is displayed by using r2-black and white color scheme. Black represents very high LD (r2 = 0.8-1), and white indicates the absence of correlation (r2 = 0-0.2) between SNPs. (B) The two tSNPs and SNPs that are indirectly measured by them are listed with corresponding r2-values. Major and minor alleles of the selected tSNPs are given with their frequencies, based on the HapMap data for the CHB population.Back to article page