Table 4 Metabolic and hormonal measurements on ACTH test day

ACTH, pM

1.4 (3.1)

2.4 (2.6)

1.9 (7.5)

4.1 (3.9)

0.37, 0.10, 0.22

Cholesterol, mM

1.3 (0.8)

1.8 (1.2)

2.4 (1.8)

2.8 (1.0)

< 0.001, 0.02, 0.75

HDL-cholesterol, mM

0.40 (0.40)

0.60 (0.60)

0.80 (0.80)

0.90 (0.60)

0.06, 0.18, 0.17

Progesterone, nM

0.40 (0.90)

0.50 (0.70)

1.0 (1.0)

0.60 (0.70)

0.55, 0.34, 0.16

Corticosterone, nM

3.4 (4.9)

3.5 (6.4)

5.3 (4.6)

4.0 (7.4)

0.23, 0.04, 0.64

Aldosterone, nM

1.3 (1.3)

0.70 (1.3)

0.50 (0.1)

1.2 (0.7)

0.08, 0.13, 0.007

17-OH-progesterone, nM

2.9 (2.8)

2.6 (1.5)

3.9 (2.1)

2.5 (2.4)

0.48, 0.09, < 0.001

11ß-deoxycortisol, nM

15 (58)

3.1 (8.3)

34 (30)

3.7 (3.3)

0.003, < 0.001, < 0.001

Cortisol, nM

460 (200)

500 (221)

325 (134)

455 (335)

0.03, 0.98, 0.04

Cortisol/11ß-deoxycortiso

l26 (175)

157 (352)

12 (28)

316 (380)

0.04, < 0.001, < 0.001

Cortisol/ACTH

209 (340)

223 (229)

171 (270)

109 (80)

0.07, 0.08, 0.08

Cortisol increase, nM

220 (190)

298 (315)

165 (169)

395 (238)

0.04, < 0.001, 0.98

6 (54)

14 (44)

2 (67)

6 (29)

0.92, 0.17, 0.43

DHEA, μM

6.1 (4.6)

6.4 (4.9)

6.1 (1.8)

5.9 (4.1)

0.61, 0.61, 0.44

DHEAS, nM

0.70 (1.4)

0.48 (0.76)

0.50 (4.2)

0.90 (1.1)

0.39, 0.03, 0.87

Androstenedione, nM

3.8 (8.6)

2.4 (2.9)

3.6 (2.8)

2.8 (2.4)

0.13, 0.02, 0.60