| |
RCA (n= 152)
|
Heparin (n= 73)
|
No AC (n= 77)
|
|---|
|
CIRCUIT LIFETIME
| | | |
|
Mean ± SD (hours)
|
49.8 ± 35.4***
|
30.6 ± 24.3
|
25.7 ± 21.2
|
|
Median (hours)
|
41
|
22
|
20
|
|
> 24 hours
|
74%
|
45%
|
40%
|
|
> 48 hours
|
41%
|
25%
|
14%
|
|
> 72 hours
|
27%
|
12%
|
5%
|
|
CRRT STOPPING CAUSES
| | | |
|
CVC malfunction
|
34.9%
|
17.8%
|
15.6%
|
|
Alarm handling/technical issues
|
23.7%
|
12.3%
|
2.6%
|
|
Scheduled
|
19.7%
|
0%
|
1.3%
|
|
Medical procedures
|
13.8%
|
2.8%
|
3.9%
|
|
Clotting
|
0%
|
61.6%
|
68.8%
|
|
Unidentified
|
7.9%
|
5.5%
|
7.8%
|
|
DIALYSIS DOSE
a
| | | |
|
Prescribed dose (ml/kg/hour)
|
26.8 ± 3.8
|
27.3 ± 4.7
|
26.6 ± 7.1
|
|
Delivered dose (ml/kg/hour)
|
25.6 ± 4.9**
|
23.7 ± 7.2
|
23.1 ± 8
|
|
Delta dose (%)
|
4.7 ± 12.1***
|
13 ± 20.5
|
12.7 ± 19.1
|
- Data are expressed as mean ± SD or percentage. aCorrected for predilution. Statistical comparison among different anticoagulation modalities: ANOVA with Bonferroni post-hoc test. ***P < 0.0001; **P < 0.02. AC, anticoagulation; ANOVA, analysis of variance; CRRT, continuous renal replacement therapy; CVC, central venous catheter; n, number; RCA, regional citrate anticoagulation; SD, standard deviation.
