Figure 3From: Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patientsComparison of creatinine clearance (CCl) with plasma creatinine (pCr) on entry into the ICU in the (A) known baseline cohort and (B) entire cohort. Dashed lines represent optimum cut-points for diagnosis of acute kidney injury (AKI) according to a change in CCl (CCl < 48.6 ml/min) or change in pCr (pCr > 1.24 mg/dl). (A) The four possible diagnoses (i) No AKI (ΔpCrNo-AKI and ΔCClNo-AKI), (ii) AKI by the clearance criterion only (ΔpCrNo-AKI and ΔCClAKI), (iii) AKI by the pCr criterion only (ΔpCrAKI and ΔCClNo-AKI) or (iv) AKI by both criteria (ΔpCrAKI and ΔCClAKI) are illustrated by squares for ΔpCrAKI and closed circles or squares for ΔCClAKI. (B) Oliguric (urine output < 0.5 ml/kg/h average over 4 h, closed circles), and non-oliguric (open circles) for the entire cohort. No-AKI (CClNo-AKI): without AKI; ΔpCr: relative change in pCr from baseline; ΔCCl: relative change in CCl from Cockcroft-Gault (CG) baseline; AKI (pCrAKI): with AKI.Back to article page