Table 2 Propensity score-matched patients with and without candidemia.
Without candidemia (number = 70) | With candidemia (number = 35) | P | SDT | |
|---|---|---|---|---|
Age, years, mean (SD) | 60.96 ± 17.3 | 59.2 ± 18.36 | .641 | 9.86% |
Male/female (%) | 24 (34.3) | 12 (34.3) | 1 | 0% |
APACHE II score at ICU admission, mean (SD) | 19.07 ± 6.34 | 19.88 ± 6.29 | .532 | -12.82% |
SOFA score at ICU admission | 8 (4 to 10) | 8 (7 to 10) | .658 | |
ICU length of stay (days)a | 28.5 (17.75 to 40.25) | 30 (17 to 58) | .514 | |
Hospital length of stay (dys)a | 43 (28 to 69) | 37 (27 to 70) | .801 | |
ICU mortality, number (%) | 26 (37.1) | 18 (51.4) | .163 | |
Overall mortality, number (%) | 35 (50) | 19 (54.3) | .680 | |
Diagnosis on ICU admission, number (%) | .861 | |||
Medical | 29 (41.4) | 15 (42.9) | 3% | |
Surgical | 35 (50) | 16 (45.7) | 8.61% | |
Trauma | 6 (8.6) | 4 (11.4) | -9.34% | |
Multifocal colonization, total, number (%) | 67 (95.7) | 32 (91.4) | .398 | -17.57 |
Clinical condition, number (%) at the time of ICU admission | .459 | |||
No sepsis | 6 (8.6) | 1 (2.9) | -24.67 | |
Sepsis | 17 (24.3) | 11 (31.4) | 15.89 | |
Severe sepsis | 12 (17.1) | 9 (25.7) | 21.08 | |
Septic shock | 35 (50) | 14 (40) | -20.2 | |
Surgery, number (%) | 35 (50) | 16 (45.7) | .680 | -8.6 |
Abdominal surgery, number (%) | 26 (37.1) | 11 (31.4) | .565 | -12 |
Surgical procedures, number | .961 | |||
None | 34 (48.6) | 18 (51.4) | 5.6 | |
One | 19 (27.1) | 9 (25.7) | -3.7 | |
Two or more | 17 (24.3) | 8 (22.9) | -3.29 | |
Secondary peritonitis, number (%) | 9 (12.9) | 3 (8.6) | .517 | -13.9 |
Underlying illnesses, number (%) | ||||
Neurologic disease | 12 (17.1) | 5 (14.3) | .709 | -7.7 |
Trauma | 9 (12.9) | 6 (17.1) | .556 | 11.78 |
Diabetes mellitus | 16 (22.9) | 7 (20) | .739 | -7 |
COPD | 18 (25.7) | 8 (22.9) | .749 | -6.5 |
Heart failure | 8 (11.4) | 6 (17.1) | .419 | 16.36 |
Chronic renal failure | 4 (5.7) | 2 (5.7) | 1 | 0 |
Acute coronary syndrome | 1 (1.4) | 1 (2.9) | 1 | 0 |
Chronic liver failure | 3 (4.3) | 0 | .549 | -29.97 |
Hematologic malignancy | 1 (1.4) | 0 | 1 | -16.85 |
Solid tumor | 7 (10) | 4 (11.4) | 1 | -4.5 |
Risk factors, number (%) | ||||
Urinary catheter | 70 (100) | 34 (97.1) | .333 | -24.4 |
Central venous catheter | 70 (100) | 35 (100) | - | 0 |
Mechanical ventilation | 69 (98.6) | 35 (100) | 1 | 16.8 |
Broad-spectrum antibiotics | 69 (98.6) | 34 (97.1) | 1 | -10.35 |
Empiric/preemptive antifungal treatment. | 5 (7.1) | 2 (5.7) | 1 | 5.7 |
Arterial catheter | 70 (100) | 34 (97.1) | .333 | -24.4 |
Enteral nutrition | 49 (70) | 25 (71.4) | .880 | 3 |
Total parenteral nutrition | 55 (78.6) | 25 (71.4) | .418 | -16.78 |
Corticosteroids | 31 (44.3) | 12 (34.3) | .326 | -20.58 |
Renal replacement therapy | 24 (34.3) | 14 (40) | .566 | 11.8 |