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Figure 2 | Critical Care

Figure 2

From: Blood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study

Figure 2

Transfusion of stored red blood cells significantly increases plasma free hemoglobin and nitric oxide consumption. (A) Course of plasma free hemoglobin (fHb) in patients receiving 1 (white bars) or 2 (grey bars) packed red blood cell (pRBC) units from baseline levels before blood transfusion (BT) to 15, 30, 60 and 120 minutes and 24 hours after BT. ***Significant changes of fHb levels within groups compared with baseline fHb concentrations; P < 0.001. (B) Course of plasma nitric oxide (NO) consumption in a random selection of four patients transfused with 1 pRBC unit and nine patients transfused with 2 pRBC units. *Significant differences of fHb levels within groups compared with baseline fHb concentrations; P < 0.05.

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