From: Plasma sRAGE enables prediction of acute lung injury after cardiac surgery in children
Variables | Before surgery | Before CPB | After CPB | 1 hour after surgery | 12 hours after surgery | 24 hours after surgery |
---|---|---|---|---|---|---|
PaO2 (mm Hg) |  | 191.5 ± 60.5 | 185.3 ± 77.2 | 156.2 ± 40.4 | 146.2 ± 39.3 | 111.4 ± 20.8 |
PaCO2 (mm Hg) |  | 34.4 ± 4.5 | 40.5 ± 7.4 | 36.6 ± 5.7 | 37.1 ± 4.6 | 37.2 ± 5.2 |
FiO2 | Room air | 0.47 ± 0.9 | 0.60 ± 0.19 | 0.50 ± 0.04 | 0.45 ± 0.1 | 0.33 ± 0.15 |
Total protein (g/L) | 63.74 ± 4.76 | 51.99 ± 4.05 | 49.76 ± 4.78a | 51 ± 4.35b | 55.4 ± 5.47c | 55.18 ± 6.35d, e |
sRAGE (pg/ml) | 821.28 ± 267.93 | 995.11 ± 568.81 | 2,073.91 ± 911.82a | 1,587.15 ± 657.35b, f | 753.74 ± 460.27c, g | 508.38 ± 270.03d, e |
sRAGEN (pg/mg) | 12.91 ± 4.3 | 20 ± 12.12 | 41.8 ± 18.25a | 31.52 ± 13.75b, f | 13.87 ± 8.81g | 9.4 ± 5.3d, e |
S100A12 (ng/ml) | 16.32 ± 11.92 | 22.89 ± 15.20 | 176.69 ± 70.53a | 193.04 ± 62.56b | 198.13 ± 71.45c | 176.19 ± 78.43d |
S100A12N (pg/mg) | 255.3 ± 185.8 | 458.49 ± 298.74 | 3,570.99 ± 1,473.74a | 3,805.61 ± 1,296.3b | 3,593.58 ± 1,309.83c | 3,474.96 ± 1,254.31d |