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Table 2 Time spent with normal ventilation, ventilation pattern, peak airway pressure, PEtCO2 and SpO2

From: A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase

 

PSV_before

ASV

ASV-CO2

ASV-CO2-O2

PSV_after

P value

Normal ventilation (% of the recording time)

93 (82 to 95)

94 (82 to 96)

95 (92 to 96)

95 (89 to 96)

97 (85 to 100)

NS

Number of ventilation setting changes/patient

0 (0 to 0)

0 (0 to 0)

78 (58 to 119)

81 (35 to 250)

0 (0 to 0)

< 0.001*

Respiratory rate (breaths/minute)

17 (14 to 21)

21 (18 to 24)

23 (19 to 25)

22 (18 to 27)

20 (16 to 26)

NS

Tidal volume (ml/kg)

8.3 (7.1 to 9.3)

8.7 (7.7 to 9.7)

8.9 (8.2 to 9.7)

8.4 (7.8 to 9.7)

7.9 (6.7 to 8.9)

NS

Paw-peak (cmH2O)

16 (15 to 18)

15 (14 to 22)

16 (14 to 19)

17 (15 to 21)

15 (14 to 19)

NS

PEtCO2 (mmHg)

-

43 (39 to 45)

43 (40 to 45)

43 (39 to 47)

-

NS

SpO2 (%)

-

98 (95 to 100)

99 (96 to 100)

98 (95 to 100)

-

NS

  1. Results of time spent with normal ventilation, ventilation pattern, peak airway pressure, partial pressure of end-tidal CO2 (PEtCO2) and pulse oxygen saturation (SpO2) during the five 1-hour periods investigated. Results given as the median with 25% to 75% interquartile range. Normal ventilation is the percentage of time with normal breath as defined by 10 breaths/minute < respiratory rate < 40 breaths/minute, tidal volume > 5 ml/kg predicted body weight and 25 mmHg < PEtCO2 < 55 mmHg. PSV, pressure support ventilation; ASV, adaptive support ventilation, ASV-CO2, ASV plus the CO2 controller; ASV-CO2-O2, ASV-CO2 plus the oxygen controller; Paw-peak, peak proximal airway pressure; NS, P > 0.05. *P < 0.001 for ASV versus ASV-CO2 and for ASV versus ASV-CO2-O2.
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Critical Care

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