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Figure 2 | Critical Care

Figure 2

From: A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase

Figure 2

Functional algorithm of the ventilation and oxygen controller. (A) Ventilation controller. The partial pressure in end-tidal CO2 (PEtCO2) values are given with the quality index and derived from the mainstream CO2 sensor with proprietary algorithms as a surrogate of arterial partial pressure of CO2. PEtCO2min and PEtCO2max are adjustable by the user and depend on the patient's severity estimated by the level of inspiratory pressure; that is, the higher the inspiratory pressure and the more permissive the PEtCO2 limits. As an example and by default for an inspiratory pressure of 10 cmH2O, PEtCO2min is 35 mmHg and PEtCO2max is 41 mmHg. (B) Oxygen controller. The oxygen saturation from pulse oxymetry (SpO2) limits (SpO2safety and SpO2min) are adjustable by the user and depending on the patient's severity estimated by the positive end-expiratory pressure (PEEP) level; that is, the higher the PEEP level and the more permissive the SpO2 limits. As an example and by default for a PEEP level of 5 cmH2O, SpO2safety is 88%, SpO2min is 93% and SPO2max is 98%. The PEEPopt is defined according to a PEEP-fraction of inspired oxygen (FiO2) table and PEEPmax set by the user. The patient SpO2 is provided with a quality index and is derived from the pulse oxymeter with proprietary algorithms for artefact and motion rejections. MV, minute ventilation; RR, respiratory rate.

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