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Table 3 Comparison of initial patient data grouped according to improvement or deterioration of clinical conditions

From: Early neurovascular uncoupling in the brain during community acquired pneumonia

Acute-phase examination

Patients who recovered

(n= 24)

Patients who deteriorated (n= 7)

Statistics

RR mean, mm Hg

83 ± 13

84 ± 12

NS

Body mass index

28 ± 6

24 ± 4

NS

Smoking, pack-years

31 ± 13

57 ± 20

NS

Diabetes, percentage

14

33

NS

Coronary artery disease, percentage

29

100

P < 0.05

pH

7.37 ± 0.06

7.33 ± 0.04

P = 0.07

Leukocytes, g/L

11 ± 5

11 ± 5

NS

Temperature,°C

36.8 ± 0.6

36.3 ± 0.3

P = 0.07

ATS score

3 ± 0.8

3 ± 0.8

NS

PSI score

101 ± 23

125 ± 13

P < 0.05

CURB-65 score

1.6 ± 0.9

2.0 ± 0.6

NS

APACHE II score

13 ± 4

15 ± 2

P = 0.06

GCS score

15 ± 0.3

14 ± 0.8

P < 0.05

ICDSC score

3 ± 1

3 ± 1

NS

ACE/AT inhibitors, percentage

36

66

NS

Calcium antagonists, percentage

18

17

NS

Beta-blocker, percentage

32

66

NS

Diuretics, percentage

77

100

NS

Statins, percentage

14

33

NS

Thrombo inhibitors, percentage

32

66

NS

Glucocorticoids, percentage

41

33

NS

β2 mimetics, percentage

64

83

NS

Theophylline, percentage

23

17

NS

EEG μV2 delta

83 ± 74

68 ± 43

NS

EEG μV2 theta

60 ± 64

43 ± 41

NS

EEG μV2 alpha

122 ± 131

77 ± 65

NS

EEG μV2 beta

42 ± 27

29 ± 15

NS

EEG percentage delta

30 ± 16

31 ± 11

NS

EEG percentage theta

19 ± 12

19 ± 14

NS

EEG percentage alpha

35 ± 17

33 ± 17

NS

EEG percentage beta

16 ± 7

17 ± 9

NS

EEG peak Hz delta

1.2 ± 0.4

1.3 ± 0.3

NS

EEG peak Hz theta

6.6 ± 0.9

6.3 ± 1

NS

EEG peak Hz alpha

9.3 ± 0.9

9.7 ± 0.9

NS

EEG peak Hz beta

15 ± 2

16.4 ± 2.5

NS

Visual evoked potential, μV

7.4 ± 2.3

7.1 ± 2.8

NS

Resting flow velocity, cm/second

47 ± 14

48 ± 17

NS

Gain, percentage

15 ± 4

9 ± 3

P < 0.05

Natural frequency, 1/second

0.21 ± 0.03

0.22 ± 0.08

NS

Attenuation

0.41 ± 0.19

0.31 ± 0.27

NS

Rate time, seconds

1.6 ± 1.3

0.9 ± 0.3

NS

  1. Data are presented as mean ± standard deviation unless indicated otherwise. ACE, angiotensin-converting enzyme; APACHE II, Acute Physiology and Chronic Health Evaluation II; AT, angiotensin; ATS, American Thoracic Society Scale; CURB-65, confusion of new onset (defined as an abbreviated mental test score of 8 or less), urea of greater than 7 mmol/L (19 mg/dL), respiratory rate of 30 breaths per minute or greater, systolic blood pressure of less than 90 mm Hg or diastolic blood pressure of 60 mm Hg or less, and age of at least 65 years; EEG, electroencephalogram; GCS, Glasgow Coma Scale; ICDSC, Intensive Care Delirium Screening Checklist; NS, not significant; PSI, pneumonia severity index; RR, blood pressure.
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