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Table 4 Hyperemic velocity in survivors versus nonsurvivors: stratified analysisa

From: Brachial artery reactivity in patients with severe sepsis: an observational study

Covariable Survivors Nonsurvivors P b
Age    
   ≤ 62 38 (29-52, n = 45 16 (14-22), n = 4 0.005
   > 62 39 (32-48), n = 33 25 (21-28), n = 13 0.003
Gender    
   Men 37 (29-46), n = 43 19 (15-22), n = 6 0.001
   Women 42 (30-52), n = 35 26 (17-28), n = 11 0.009
Hypertension    
   Yes 38 (27-49), n = 44 25 (16-28), n = 15 0.001
   No 39 (30-51), n = 34 17 (12-21), n = 2 0.027
Diabetes mellitus    
   Yes 38 (26-53), n = 18 17 (15-22), n = 9 < 0.001
   No 39 (30-48), n = 60 28 (26-34), n = 8 0.054c
Hyperlipidemia    
   Yes 36 (26-46), n = 26 22 (16-28), n = 8 0.024
   No 39 (30-51), n = 52 25 (16-27), n = 9 < 0.001
Active smoking    
   Yes 38 (30-53), n = 20 16 (12-28), n = 3 0.022
   No 39 (30-48), n = 58 25 (17-28), n = 14 < 0.001
Coronary artery disease    
   Yes 39 (32-46), n = 13 19 (14-24), n = 4 0.007
   No 38 (29-51), n = 65 25 (17-28), n = 25 0.001
Pressors    
   Yes 36 (25-44), n = 19 19 (13-28), n = 8 0.03
   No 39 (30-51), n = 59 25 (21-28), n = 9 0.001
Blood pressure    
   MAP ≤ 80 mm Hg 37 (29-46), n = 37 17 (14-27), n = 11 0.001
   MAP > 80 mm Hg 41 (30-51), n = 41 26 (22-29), n = 6 0.018
Charlson index    
   ≤ 3 37 (29-51), n = 47 25 (17-34), n = 8 0.020
   > 3 42 (30-48), n = 31 22 (15-27), n = 9 0.001
  1. MAP, mean arterial pressure at the time of brachial artery reactivity measurements; n/a, not applicable. aContinuous variables were dichotomized according to their median value (in the severe sepsis patients alone) for this analysis. bP value refers to the comparison of HV between survivors and nonsurvivors within the specified subgroup. The borderline statistical significance in this group suggested an interaction between diabetes mellitus and HV in predicting hospital mortality was possible (see Methods). However, the test for interaction [42] was insignificant (P > 0.20).