Table 1 Baseline demographic and clinical characteristics
Parameter | Placebo | Inhaled NO | P Value | |
|---|---|---|---|---|
Age, years | N | 41 | 51 | |
Mean ± SD | 47.8 ± 16.7 | 45.3 ± 15.3 | 0.494 | |
Range | 18.4 - 84.0 | 16.8 - 77.9 | ||
Sex, n (%) | Male | 19 (46%) | 25 (49%) | 0.836 |
Female | 22 (54%) | 26 (51%) | ||
Race, n (%) | Caucasian | 35 (85%) | 42 (82%) | 0.847 |
Black | 4 (10%) | 5 (10%) | ||
Other | 2 (5%) | 4 (8%) | ||
Height, cm | N | 39 | 51 | |
Mean ± SD | 168.7 ± 11.4 | 169.4 ± 9.2 | 0.912 | |
Weight, kg | N | 41 | 51 | |
Mean ± SD | 85.7 ± 24.1 | 76.4 ± 19.2 | 0.049 | |
BW ≥ 35% IBW | N | 19 (46.3%) | 13 (25.5%) | 0.028 |
Causes of ARDS,a n (%) | ||||
Pneumonia | 20 (49%) | 15 (29%) | 0.084 | |
Toxic gas inhalation | 0 (0%) | 0 (0%) | 1.000 | |
Acute pancreatitis | 1 (2%) | 3 (6%) | 0.626 | |
Massive blood transfusion | 5 (12%) | 10 (20%) | 0.404 | |
Fat emboli | 1 (2%) | 2 (4%) | 1.000 | |
Aspiration pneumonitis | 9 (22%) | 9 (18%) | 0.610 | |
Pulmonary contusion | 6 (15%) | 12 (24%) | 0.307 | |
Postpartum ARDS | 2 (5%) | 0 (0%) | 0.196 | |
Multiple trauma | 14 (34%) | 15 (29%) | 0.657 | |
Elective or emergency surgical procedures | 9 (22%) | 20 (39%) | 0.114 | |
Patient History, n (%) | ||||
Preexisting steroid use | 3 (7%) | 8 (15%) | 0.334 | |
Asthma | 4 (10%) | 5 (10%) | 1.000 | |
COPD | 6 (15%) | 6 (12%) | 0.761 | |
Tobacco use | 17 (41%) | 26 (51%) | 0.405 | |