Table 1 The bundle of 10 recommendations
Recommendations | |
|---|---|
# 1 | Initial bacteriological samples drawn from sites that are suspected as the source of infection blood cultures in the first three hours |
# 2 | Initiating an empirical antibiotics therapy in the first three hours |
# 3 | Measurement of arterial lactate within the first six hours |
# 4 | Volume expansion ≥20 ml/kg within the first six hours |
# 5 | A targeted MAP > 65 mmHg within the first six hours |
# 6 | Assessments of CVP and ScvO2 within the first six hours |
# 7 | Glucose control ≤8.3 mmol/l within the first 24 hours |
# 8 | Low doses of corticosteroids when norepinephrine requirement at fewer than six hours |
# 9 | Using low tidal volume (≤8ml/kg of ideal body weight) |
# 10 | Adequate use of rhAPC within the first 24 hours |