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Table 4 Hospital mortality relative to initial antimicrobial adequacy

From: Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial

Adequacy

No. of deaths/episodes (%)

P

Overall (n = 54)

 

0.304

   Inadequate

6/20 (30%)

 

   Adequate

15/34 (44.1%)

 

Gram-positive organism (n = 35)

 

0.476

   Inadequate

4/12 (33.3%)

 

   Adequate

12/23 (52.2%)

 

Gram-negative bacilli (n = 28)

 

0.639

   Inadequate

1/7 (14.3%)

 

   Adequate

6/21 (28.6%)

 
  1. Excluding culture-negative patients.
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Critical Care

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