Table 2 Haemodynamic changes

PAP (mmHg)

14.7 ± 0.7

18.4 ± 0.7

24.7 ± 0.7

27.0 ± 0.6

30.7 ± 0.7

37.0 ± 0.7^{a, b, c}

(10 to 19)

(4 to 28)

(9 to 60)

(5 to 47)

(6 to 62)

(13 to 89)

MAP (mmHg)

108.3 ± 2.2

107.3 ± 2.3

110.6 ± 2.3

90.0 ± 2.0

89.0 ± 2.3

98.1 ± 2.3^{a, c}

(67 to 146)

(64 to 172)

(55 to 155)

(37 to 130)

(44 to 169)

(30 to 149)

CVP (mmHg)

6.0 ± 0.6

5.1 ± 0.6

5.5 ± 0.6

5.7 ± 0.6

4.8 ± 0.6

5.2 ± 0.6^a

(1 to 20)

(0 to 13)

(0 to 20)

(0 to 17)

(0 to 18)

(1 to 18)

Heart rate (bpm)

102.5 ± 2.9

112.9 ± 3.0

113.7 ± 3.0

111.4 ± 2.7

121.8 ± 3.0

122.6 ± 3.0^a

(65 to 147)

(60 to 132)

(70 to 192)

(52 to 210)

(57 to 182)

(65 to 166)

O₂sat (%)

97.2 ± 0.6

97.7 ± 0.7

96.8 ± 0.7

94.9 ± 0.6

95.4 ± 0.7

94.5 ± 0.7^a

(81 to 100)

(80 to 100)

(86 to 100)

(69 to 100)

(73 to 100)

(71 to 100)

EtCO₂ (mmHg)

32.9 ± 1.2

32.5 ± 1.2

30.6 ± 1.2

34.0 ± 1.2

33.6 ± 1.2

31.7 ± 1.2

(20 to 47)

(23 to 39)

(10 to 44)

(13 to 54)

(17 to 52)

(15 to 55)

CO (L/min)

4.6 ± 0.2

4.6 ± 0.2

3.7 ± 0.2

4.5 ± 0.2

4.5 ± 0.2

3.6 ± 0.2^{a, b, c}

(3.1 to 6.6)

(3.5 to 6.0)

(1.8 to 7.2)

(1.1 to 7.1)

(1.1 to 5.8)

(1.4 to 5.0)

SvO₂ (%)

70.2 ± 1.5

73.3 ± 1.5

65.9 ± 1.5

72.5 ± 1.4

75.6 ± 1.5

68.3 ± 1.5^a

(44 to 82)

(33 to 81)

(38 to 84)

(48 to 91)

(48 to 86)

(22 to 77)

Body temperature (°C)

38.7 ± 0.1

38.5 ± 0.1

38.7 ± 0.1

38.7 ± 0.1

38.5 ± 0.1

38.7 ± 0.1

(38.1 to 39.8)

(37.2 to 40.2)

(38.0 to 39.4)

(38.0 to 41.4)

(37.1 to 41.5)

(37.7 to 41.1)

PaO₂ (mmHg)

184.8 ± 11.9

193.2 ± 13.0

152.6 ± 13.1

131.1 ± 7.4

139.5 ± 13.2

98.9 ± 13.2^{a, b, c}

(122 to 216)

(76.5 to 210)

(72.2 to 205)

(94.8 to 215)

(64.8 to 233)

(50.0 to 210)

PaCO₂ (mmHg)

37.7 ± 2.0

37.0 ± 2.2

39.3 ± 2.2

39.8 ± 1.4

39.1 ± 2.1

41.4 ± 2.2^a

(30.5 to 42.3)

(24.9 to 40.6)

(22.7 to 51.5)

(28.5 to 54.5)

(23.7 to 51.9)

(27.7 to 70.6)

C_stat (L/kPa)

38.4 ± 3.7

35.1 ± 4.0

30.4 ± 4.0

27.4 ± 2.5

24.1 ± 4.0

19.4 ± 4.0^{a, b, c}

(26.3 to 63.6)

(22.3 to 39.0)

(15.9 to 43.6)

(14.2 to 73.3)

(12.0 to 65.0)

(9.3 to 66.7)

PaO₂/FiO₂ (FiO₂ = 40%)

462.0 ± 11.9

483.0 ± 13.0

381.5 ± 13.1

327.8 ± 7.4

348.8 ± 13.2

247.3 ± 13.2^{a, b, c}

(305 to 540)

(191 to 525)

(181 to 513)

(237 to 537)

(162 to 583)

(125 to 525)