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Table 4 Detailed calculations of the urinary excretion

From: Low doses of esmolol and phenylephrine act as diuretics during intravenous anesthesia

Measured parameters

Controls

(n= 20)

Esmolol

(n= 20)

Phenylephrine

(n= 20)

Kruskal-

Wallis test

Infused volume, mL

1,000 (950-1,100)

1,060 (985-1,180)

1,090 (970-1,190)

NS

Cumulative urine volume, mL

    

   40 minutes

13 (3-38)

26 (8-58)

54 (25-91)

NS

   60 minutes

36 (15-99)

71 (43-150)

135 (58-195)

P < 0.05

   120 minutes

81 (45-200)

194 (119-352)

236 (97-353)

P < 0.01

   180 minutes

93 (53-226)

237 (136-416)

276 (168-375)

P < 0.01

   Non-surgery

43 (27-142)

147 (73-228)

176 (88-285)

P < 0.03

   Surgery

34 (24-53)

65 (46-122)

61 (39-129)

P < 0.04

Urine flow, mL/minute

    

   0-180 minutes

0.51 (0.29-1.22)

1.30 (0.76-2.31)

1.53 (0.93-2.05)

P < 0.01

   Non-surgery

0.50 (0.25-1.18)

1.33 (0.95-2.63)

1.72 (0.86-2.70)

P < 0.01

   Surgery

0.51 (0.33-0.83)

0.77 (0.54-1.51)

0.80 (0.54-1.34)

NSa

   Excreted/infused at 180 minutes, percentage

8.8 (4.9-20.2)

20.4 (13.8-38.0)

25.4 (14.9-36.4)

P < 0.01

  1. Data are the median (25th to 75th percentiles). aP = 0.11; esmolol versus controls P < 0.05 (Mann-Whitney test). NS, not significant.