Relationship between thyroid function and ICU mortality: a prospective observation study

Table 2 Performance of variables in predicting ICU mortality^a

Variable	AUC ROC	P value	Cutoff value	Sensitivity (%)	Specificity (%)
TT3	0.722 ± 0.33	< 0.001	≤ 0.965	71.28	63.74
TT4	0.680 ± 0.031	< 0.001	≤ 7.04	57.18	72.53
FT3	0.762 ± 0.028	< 0.001	≤ 3.33	62.14	78.02
FT4	0.625 ± 0.035	< 0.001	≤ 13.63	74.93	49.46
rT3	0.529 ± 0.035	0.405
TSH	0.603 ± 0.034	0.002	≤ 0.815	54.04	71.33
T3/rT3	0.617 ± 0.035	0.001	≤ 2.31	72.53	45.79
APACHE II score	0.829 ± 0.022	< 0.001	≥ 15	74.22	75.00
NT-proBNP	0.724 ± 0.030	< 0.001	≥ 5191	73.07	68.54
CRP	0.689 ± 0.030	< 0.001	≥ 66.5	69.66	61.11

^aAUC ROC, area under the receiver operating characteristic curve; APACHE II score, Acute Physiology and Chronic Health Evaluation II score; CRP, C-reactive protein; FT3, free triiodothyronine; FT4, free thyroxine; NT-proBNP, N-terminal pro-brain natriuretic peptide; rT3, reverse triiodothyronine; TSH, thyroid-stimulating-hormone; TT3, total triiodothyronine; TT4, total thyroxine; T3/rT3, the ratio of rT3 to T3.

ISSN: 1364-8535