Skip to main content

Table 1 COXa/CSa and COXq/CSa ratios according to mitochondrial DNA haplogroup

From: Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup

  Haplogroup  
  HV U JT No R P value
Time of diagnosis (n = 44) (n = 24) (n = 15) (n = 13)  
   COXa/CSa ratio 2.83 (2.34 to 3.17) 2.90 (2.24 to 3.17) 3.25 (2.63 to 3.56) 2.81 (2.39 to 3.09) 0.28
   COXq/CSa ratio 1.71 (1.26 to 2.90) 1.89 (1.18 to 2.85) 2.72 (1.57 to 3.38) 2.23 (1.31 to 3.31) 0.41
Day 4 (n = 34) (n = 18) (n = 10) (n = 10)  
   COXa/CSa ratio 2.73 (2.41 to 3.30) 2.93 (2.45 to 3.16) 3.24 (3.04 to 3.33) 2.85 (2.39 to 3.04) 0.10
   COXq/CSa ratio 1.53 (1.26 to 2.99) 2.14 (1.34 to 3.18) 3.10 (2.52 to 3.45) 2.51 (1.23 to 3.34) 0.04
Day 8 (n = 32) (n = 14) (n = 10) (n = 9)  
   COXa/CSa ratio 2.68 (2.22 to 3.23) 2.72 (2.39 to 3.23) 3.07 (2.83 to 3.15) 3.04 (2.32 to 3.41) 0.41
   COXq/CSa ratio 1.59 (1.19 to 3.06) 1.63 (1.21 to 2.79) 3.39 (2.61 to 3.52) 2.91 (1.24 to 3.44) 0.02
  1. Data presented as median (interquartile range). COXa/CSa, cytochrome c oxidase specific activity/citrate synthase specific activity; COXq/CSa, cytochrome c oxidase quantity/citrate synthase specific activity.