Skip to main content

Red blood transfusion is a predictor of poor outcome in pediatric cardiac surgery

Introduction

Red blood cell transfusion is associated with morbidity and mortality among adults undergoing cardiac surgery. We aimed to evaluate the association of transfusion with morbidity in pediatric cardiac surgical patients. The purpose of this study was to assess whether red blood cell transfusions result in worse outcomes after cardiac surgery in pediatric patients.

Methods

We studied an observational and prospective cohort of 200 patients undergoing cardiac surgery for congenital heart disease. We recorded baseline characteristics, RACHS-1 score, intraoperative data, cardiopulmonary bypass length, type of surgery, transfusion requirement and postoperative complications as need for reoperation, time of mechanical ventilation, cardiovascular complications, acute renal failure, infection, readmission at ICU and death during 28 days.

Results

One hundred and twenty-four patients were exposed to blood components. Seventy-seven percent of patients presented at least one major complication. There was no difference between transfused and nontransfused patients regarding baseline or intraoperative characteristics. Transfused patients presented a higher incidence of major complications than nontransfused patients (93.5% vs. 54.5%, P = 0.002). In a multivariate analysis, red blood cell transfusion was an independent risk factor for clinical complications including death in 28 days (OR = 2.2 (95% CI 1.4 to 23.4)).

Conclusion

Blood transfusion after pediatric cardiac surgery is a risk factor for worse outcome. Avoiding blood transfusion may reduce mortality in this population.

Author information

Affiliations

Authors

Corresponding author

Correspondence to C Colognesi.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Cite this article

Colognesi, C., Maia, R., Hajjar, L. et al. Red blood transfusion is a predictor of poor outcome in pediatric cardiac surgery. Crit Care 16, P443 (2012). https://doi.org/10.1186/cc11050

Download citation

Keywords

  • Blood Transfusion
  • Congenital Heart Disease
  • Acute Renal Failure
  • Major Complication
  • Cardiopulmonary Bypass