Table 1 Differences between HYPOLYTE and CRASH studies
From: Glucocorticoid therapy for trauma - ready for prime time?
| Â | CRASH STUDY | HYPOLYTE STUDY |
|---|---|---|
Number of patients | 10,000 | 150 |
Primary end point | Mortality | Pneumonia incidence |
Time to administration of first dose of steroid | < 8 hours | Within 36 hours of trauma; 25 hours (median) |
Steroid loading dose | 2 gms | None |
Duration of Steroids | 48 hours | 1 week |