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Table 8 The factors associated with cerebrovasospasm

From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage

 

Vasospasm

(n = 131)

Non-vasospasm

(n = 172)

P value

Sex (male/female)

61/70

70/102

0.307

Age (y)

43.8 ± 12.2

43.9 ± 12.5

0.973

WFNS score on admission

3.2 ± 1.1

1.7 ± 0.9

<0.001

Modified Fisher score on admission

3.5 ± 1.0

2.2 ± 0.6

<0.001

Aneurysmal location

  

0.813

   Posterior communication artery

33 (25.2%)

50 (29.1%)

 

   Internal carotid artery

20 (15.3%)

23(13.4%)

 

   Anterior communication artery

29 (22.1%)

37 (21.5%)

 

   Middle cerebral artery

22 (16.8%)

23 (13.4%)

 

   Anterior cerebral artery

16 (12.2%)

19 (11.0%)

 

   Posterior cerebral artery

7 (5.3%)

16 (9.3%)

 

   Vertebral artery

4 (3.1%)

4 (2.3%)

 

Surgery

86 (65.5%)

100 (58.1%)

0.183

Aneurysmal size (mm)

9.1 ± 5.7

5.8 ± 3.5

<0.001

Rebleeding

10 (7.6%)

6 (3.5%)

0.110

Acute hydrocephalus

71 (54.2%)

19 (11.0%)

<0.001

Intracerebral hemorrhage

26 (19.9%)

13(7.6%)

0.002

Intraventricular hemorrhage

52 (39.7%)

20 (11.6%)

<0.001

External ventricular drain

90 (68.7%)

19 (11.0%)

<0.001

Admission time (hr)

4.5 ± 3.4

4.9 ± 3.8

0.342

Seizure

17 (13.0%)

27 (15.7%)

0.505

Systolic arterial pressure (mmHg)

134.2 ± 23.6

128.7 ± 21.2

0.033

Diastolic arterial pressure (mmHg)

81.1 ± 15.1

77.5 ± 13.8

0.031

Mean arterial pressure (mmHg)

98.8 ± 16.1

94.6 ± 15.3

0.020

Plasma C-reactive protein level (mg/L)

7.9 ± 3.0

6.6 ± 2.4

<0.001

plasma D-dimer level (mg/L)

2.2 ± 1.1

1.9 ± 0.9

0.011

Plasma copeptin level (pmol/L)

25.0 ± 8.4

18.3 ± 8.3

<0.001

  1. Numerical variables were presented as mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test. n indicates number of patients; WFNS, World Federation of Neurological Surgeons.