From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage
 | Vasospasm (n = 131) | Non-vasospasm (n = 172) | P value |
---|---|---|---|
Sex (male/female) | 61/70 | 70/102 | 0.307 |
Age (y) | 43.8 ± 12.2 | 43.9 ± 12.5 | 0.973 |
WFNS score on admission | 3.2 ± 1.1 | 1.7 ± 0.9 | <0.001 |
Modified Fisher score on admission | 3.5 ± 1.0 | 2.2 ± 0.6 | <0.001 |
Aneurysmal location | Â | Â | 0.813 |
   Posterior communication artery | 33 (25.2%) | 50 (29.1%) |  |
   Internal carotid artery | 20 (15.3%) | 23(13.4%) |  |
   Anterior communication artery | 29 (22.1%) | 37 (21.5%) |  |
   Middle cerebral artery | 22 (16.8%) | 23 (13.4%) |  |
   Anterior cerebral artery | 16 (12.2%) | 19 (11.0%) |  |
   Posterior cerebral artery | 7 (5.3%) | 16 (9.3%) |  |
   Vertebral artery | 4 (3.1%) | 4 (2.3%) |  |
Surgery | 86 (65.5%) | 100 (58.1%) | 0.183 |
Aneurysmal size (mm) | 9.1 ± 5.7 | 5.8 ± 3.5 | <0.001 |
Rebleeding | 10 (7.6%) | 6 (3.5%) | 0.110 |
Acute hydrocephalus | 71 (54.2%) | 19 (11.0%) | <0.001 |
Intracerebral hemorrhage | 26 (19.9%) | 13(7.6%) | 0.002 |
Intraventricular hemorrhage | 52 (39.7%) | 20 (11.6%) | <0.001 |
External ventricular drain | 90 (68.7%) | 19 (11.0%) | <0.001 |
Admission time (hr) | 4.5 ± 3.4 | 4.9 ± 3.8 | 0.342 |
Seizure | 17 (13.0%) | 27 (15.7%) | 0.505 |
Systolic arterial pressure (mmHg) | 134.2 ± 23.6 | 128.7 ± 21.2 | 0.033 |
Diastolic arterial pressure (mmHg) | 81.1 ± 15.1 | 77.5 ± 13.8 | 0.031 |
Mean arterial pressure (mmHg) | 98.8 ± 16.1 | 94.6 ± 15.3 | 0.020 |
Plasma C-reactive protein level (mg/L) | 7.9 ± 3.0 | 6.6 ± 2.4 | <0.001 |
plasma D-dimer level (mg/L) | 2.2 ± 1.1 | 1.9 ± 0.9 | 0.011 |
Plasma copeptin level (pmol/L) | 25.0 ± 8.4 | 18.3 ± 8.3 | <0.001 |