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Table 8 The factors associated with cerebrovasospasm

From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage

  Vasospasm
(n = 131)
Non-vasospasm
(n = 172)
P value
Sex (male/female) 61/70 70/102 0.307
Age (y) 43.8 ± 12.2 43.9 ± 12.5 0.973
WFNS score on admission 3.2 ± 1.1 1.7 ± 0.9 <0.001
Modified Fisher score on admission 3.5 ± 1.0 2.2 ± 0.6 <0.001
Aneurysmal location    0.813
   Posterior communication artery 33 (25.2%) 50 (29.1%)  
   Internal carotid artery 20 (15.3%) 23(13.4%)  
   Anterior communication artery 29 (22.1%) 37 (21.5%)  
   Middle cerebral artery 22 (16.8%) 23 (13.4%)  
   Anterior cerebral artery 16 (12.2%) 19 (11.0%)  
   Posterior cerebral artery 7 (5.3%) 16 (9.3%)  
   Vertebral artery 4 (3.1%) 4 (2.3%)  
Surgery 86 (65.5%) 100 (58.1%) 0.183
Aneurysmal size (mm) 9.1 ± 5.7 5.8 ± 3.5 <0.001
Rebleeding 10 (7.6%) 6 (3.5%) 0.110
Acute hydrocephalus 71 (54.2%) 19 (11.0%) <0.001
Intracerebral hemorrhage 26 (19.9%) 13(7.6%) 0.002
Intraventricular hemorrhage 52 (39.7%) 20 (11.6%) <0.001
External ventricular drain 90 (68.7%) 19 (11.0%) <0.001
Admission time (hr) 4.5 ± 3.4 4.9 ± 3.8 0.342
Seizure 17 (13.0%) 27 (15.7%) 0.505
Systolic arterial pressure (mmHg) 134.2 ± 23.6 128.7 ± 21.2 0.033
Diastolic arterial pressure (mmHg) 81.1 ± 15.1 77.5 ± 13.8 0.031
Mean arterial pressure (mmHg) 98.8 ± 16.1 94.6 ± 15.3 0.020
Plasma C-reactive protein level (mg/L) 7.9 ± 3.0 6.6 ± 2.4 <0.001
plasma D-dimer level (mg/L) 2.2 ± 1.1 1.9 ± 0.9 0.011
Plasma copeptin level (pmol/L) 25.0 ± 8.4 18.3 ± 8.3 <0.001
  1. Numerical variables were presented as mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test. n indicates number of patients; WFNS, World Federation of Neurological Surgeons.