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Table 11 The factors associated with one-year function outcome

From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage

  GOS 1-3
(n = 90)
GOS 4-5
(n = 213)
P value
Sex (male/female) 42/48 89/124 0.433
Age (y) 44.7 ± 11.3 43.5 ± 12.8 0.422
WFNS score on admission 3.6 ± 0.7 1.8 ± 0.9 <0.001
Modified Fisher score on admission 3.8 ± 0.8 2.3 ± 0.7 <0.001
Aneurysmal location    0.291
   Posterior communication artery 24 (26.7%) 59 (27.7%)  
   Internal carotid artery 13 (14.4%) 30(14.1%)  
   Anterior communication artery 17 (18.9%) 49 (23.0%)  
   Middle cerebral artery 14 (15.6%) 31 (14.6%)  
   Anterior cerebral artery 7 (7.8%) 28 (13.1%)  
   Posterior cerebral artery 11 (12.2%) 12 (5.6%)  
   Vertebral artery 4 (4.4%) 4 (1.9%)  
Surgery 54 (60.0%) 132 (62.0%) 0.747
Aneurysmal size (mm) 10.4 ± 5.8 5.9 ± 3.7 <0.001
Rebleeding 10 (11.1%) 6 (2.8%) 0.003
Acute hydrocephalus 47 (52.2%) 43 (20.2%) <0.001
Intracerebral hemorrhage 20 (22.2%) 19 (8.9%) 0.002
Intraventricular hemorrhage 59(65.6%) 12 (5.6%) <0.001
External ventricular drain 66 (73.3%) 43 (20.2%) <0.001
Angiographic vasospasm 71 (78.9%) 60 (28.2%) <0.001
Computed tomography ischemia 28 (31.1%) 22 (10.3%) <0.001
Admission time (hr) 4.5 ± 3.5 4.8 ± 3.7 0.577
Seizure 19 (21.1%) 25 (11.7%) 0.085
Plasma C-reactive protein level (mg/L) 8.2 ± 3.2 6.7 ± 2.4 <0.001
plasma D-dimer level (mg/L) 2.4 ± 1.2 1.9 ± 0.9 <0.001
Plasma copeptin level (pmol/L) 29.3 ± 9.0 17.8 ± 6.4 <0.001
  1. Numerical variables were presented as mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test. n indicates number of patients; WFNS, World Federation of Neurological Surgeons; GOS, Glasgow Outcome Scale.