From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage
 | GOS 1-3 (n = 90) | GOS 4-5 (n = 213) | P value |
---|---|---|---|
Sex (male/female) | 42/48 | 89/124 | 0.433 |
Age (y) | 44.7 ± 11.3 | 43.5 ± 12.8 | 0.422 |
WFNS score on admission | 3.6 ± 0.7 | 1.8 ± 0.9 | <0.001 |
Modified Fisher score on admission | 3.8 ± 0.8 | 2.3 ± 0.7 | <0.001 |
Aneurysmal location | Â | Â | 0.291 |
   Posterior communication artery | 24 (26.7%) | 59 (27.7%) |  |
   Internal carotid artery | 13 (14.4%) | 30(14.1%) |  |
   Anterior communication artery | 17 (18.9%) | 49 (23.0%) |  |
   Middle cerebral artery | 14 (15.6%) | 31 (14.6%) |  |
   Anterior cerebral artery | 7 (7.8%) | 28 (13.1%) |  |
   Posterior cerebral artery | 11 (12.2%) | 12 (5.6%) |  |
   Vertebral artery | 4 (4.4%) | 4 (1.9%) |  |
Surgery | 54 (60.0%) | 132 (62.0%) | 0.747 |
Aneurysmal size (mm) | 10.4 ± 5.8 | 5.9 ± 3.7 | <0.001 |
Rebleeding | 10 (11.1%) | 6 (2.8%) | 0.003 |
Acute hydrocephalus | 47 (52.2%) | 43 (20.2%) | <0.001 |
Intracerebral hemorrhage | 20 (22.2%) | 19 (8.9%) | 0.002 |
Intraventricular hemorrhage | 59(65.6%) | 12 (5.6%) | <0.001 |
External ventricular drain | 66 (73.3%) | 43 (20.2%) | <0.001 |
Angiographic vasospasm | 71 (78.9%) | 60 (28.2%) | <0.001 |
Computed tomography ischemia | 28 (31.1%) | 22 (10.3%) | <0.001 |
Admission time (hr) | 4.5 ± 3.5 | 4.8 ± 3.7 | 0.577 |
Seizure | 19 (21.1%) | 25 (11.7%) | 0.085 |
Plasma C-reactive protein level (mg/L) | 8.2 ± 3.2 | 6.7 ± 2.4 | <0.001 |
plasma D-dimer level (mg/L) | 2.4 ± 1.2 | 1.9 ± 0.9 | <0.001 |
Plasma copeptin level (pmol/L) | 29.3 ± 9.0 | 17.8 ± 6.4 | <0.001 |