Table 3 Comparison of studies for risk factors associated with invasive fungal disease
From: Risk factors for invasive fungal disease in critically ill adult patients: a systematic review
Risk factors | Studies examining risk factors (n) | Studies where risk factor was significantly associated with IFD on univariable analysis (n) | Studies where risk factor was significantly associated with IFD on multivariable analysis (n) |
|---|---|---|---|
Surgery | 7 | 5 | 5 |
Total parenteral nutrition | 6 | 6 | 4 |
Fungal colonisation | 5 | 4 | 4 |
Renal replacement therapy | 7 | 5 | 3 |
Infection/sepsis | 5 | 3 | 3 |
Mechanical ventilation | 5 | 2 | 2 |
Diabetes | 4 | 3 | 2 |
APACHE II or APACHE III score | 8 | 2 | 2 |
Central venous catheters | 7 | 4 | 1 |
Broad-spectrum antibiotics | 8 | 5 | 1 |
CPB > 120 minutes | 1 | 1 | 1 |
Red blood cell transfusions | 3 | 3 | 1 |
Antifungal medication | 4 | 2 | 1 |
Acute renal failure | 2 | 1 | 1 |
Diarrhoea | 1 | 1 | 1 |
Peripheral catheter | 1 | 1 | 1 |