Parameter | Volunteer subjects (n = 60) | Patients (n = 60) | P value |
---|---|---|---|
Age in years, mean ± standard deviation | 57.5 ± 5.7 | 57.9 ± 10.1 | 0.790 |
Men | 42 | 42 | 1.000 |
   Underlying diseases | |||
   Hypertension | 19 | 55 | ≤0.001a |
   Diabetes mellitus | 9 | 10 | 0.465 |
   Asthma | 3 | 2 | 1.000 |
   Chronic obstructive pulmonary disease | 7 | 7 | 0.778 |
   Atrial fibrillation | 10 | 5 | 0.419 |
   Coronary artery disease | 1 | 4 | 0.171 |
   Hyperlipidermia | 8 | 19 | 0.004a |
   Smoking | 17 | 34 | 0.000a |
Laboratory data at presentation, median (IQR) | |||
   White blood cell count, × 103/mL | 5.6 (4.85, 7.80) | 8.45 (6.13, 10.53) | 0.001a |
   Platelet count, × 103/mL | 245.0 (202.0, 306.5) | 206.0 (168.3, 355.8) | 0.019a |
Brain image findings at presentation | |||
   Intracerebral hemorrhage volume in cubic millimeters, median (IQR) | - | 10.0 (5.7, 25.8) | - |
   Intraventricular hematoma | - | 19 | - |
   Hydrocephalus | - | 9 | - |
   Craniotomy | - | 16 | - |
Serum adhesion molecule levels in nanograms per milliliter at presentation, median (IQR) | |||
   sL-selectin | 970.5 (844.8, 1045.1) | 759.4 (649.7, 880.4) | ≤0.001a |
   sP-selectin | 85.1 (78.4, 92.5) | 84.9 (59.2, 97.8) | 0.841 |
   sE-selectin | 39.4 (31.9, 44.6) | 40.9 (30.5, 54.1) | 0.600 |
   sICAM-1 | 183.7 (155.0, 202.2) | 205.0 (159.8, 240.0) | 0.021a |
   sVCAM-1 | 613.5 (527.4, 674.4) | 709.7 (549.5, 934.1) | 0.015a |