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Figure 3 | Critical Care

Figure 3

From: Clinical relevance of single nucleotide polymorphisms within the entire NLRP3 gene in patients with major blunt trauma

Figure 3

Effect of the rs2027432 polymorphism on the transcription activity of the NLRP3 promoter. Relative luciferase activity (RLA) was measured in human U937 cells transfected with rs2027432G or rs2027432A plasmid constructs as described in Methods. Luciferase activity was normalized for transfection efficiency by using a control plasmid, pRL-CMV. The results are expressed as fold increases in RLA of the NLRP3 promoter construct vector as compared with pGL3-Basic (means ± SD). LPS = lipopolysaccharide.

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Critical Care

ISSN: 1364-8535