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Table 2 Agreement between extrapolation from 10 CT slices and whole-lung analysis

From: Extrapolation in the analysis of lung aeration by computed tomography: a validation study

 

Normal lung CT scans

Lung CT scans with opacification

 

sheep

( n = 66)

pigs

( n = 14)

sheep

( n = 102)

pigs

( n = 41)

Vtotal (ml)

19.6 (-64.6 to 103.8)

14.5 (-26.7 to 55.8)

17.6 (-52.2 to 87.5)

1.8 (-62.9 to 66.5)

Vnon (%)

0.0 (-0.2 to 0.2)

0.0 (-0.2 to 0.2)

0.0 (-0.7 to 0.6)

0.0 (-1.2 to 1.2)

Vpoor (%)

0.0 (-0.5 to 0.5)

0.1 (-0.5 to 0.7)

-0.3 (-1.8 to 1.2)

0.1 (-1.9 to 2.0)

Vnormal (%)

0.1 (-0.8 to 0.9)

-0.1 (-0.5 to 0.4)

0.3 (-1.4 to 2.0)

-0.1 (-2.1 to 1.9)

Vhyper (%)

-0.1 (-0.7 to 0.6)

0.0 (-0.7 to 0.7)

0.0 (-0.4 to 0.5)

0.0 (-0.2 to 0.1)

Mtotal (g)

6.1 (-19.6 to 31.9)

3.3 (-11.6 to 18.2)

2.9 (-23.1 to 29.0)

1.0 (-38.1 to 40.2)

Mnon (%)

0.1 (-0.6 to 0.7)

-0.1 (-0.9 to 0.7)

0.0 (-1.4 to 1.3)

0.0 (-1.4 to 1.4)

Mpoor (%)

-0.1 (-1.1 to 1.0)

0.3 (-1.0 to 1.6)

-0.3 (-2.1 to 1.4)

0.1 (-2.0 to 2.2)

Mnormal (%)

0.0 (-1.4 to 1.4)

-0.2 (-1.4 to 1.0)

0.4 (-1.4 to 2.2)

-0.1 (-2.0 to 1.8)

Mhyper(%)

0.0 (-0.3 to 0.2)

0.0 (-0.3 to 0.3)

0.0 (-0.1 to 0.1)

0.0 (0.0 to 0.0)

Vgas (ml)

13.5 (-51.5 to 78.4)

11.2 (-25.4 to 47.8)

14.7 (-39.8 to 69.2)

0.8 (-37.7 to 39.3)

Vgas (%)

0.0 (-0.4 to 0.4)

0.0 (-0.5 to 0.6)

0.2 (-0.7 to 1.1)

-0.1 (1.2 to 1.1)

  1. Data are bias (95% limits of agreement) from the Bland-Altman analysis of the agreement between extrapolation from 10 CT slices and analysis of all CT slices covering the entire lung.
  2. CT, computed tomography; g, grams; ml, milliliters; Vgas, pulmonary gas volume; Vhyper/Mhyper, hyperaerated volume or mass; Vnomal/Mnormal, normally aerated volume or mass; Vnon/Mnon, nonaerated volume or mass; Vpoor/Mpoor, poorly aerated volume or mass; Vtotal/Mtotal, total lung volume or mass. Volumes and masses of differently aerated lung compartments were calculated as percentage of Vtotal or Mtotal, respectively.